Cleft Palate in a Newborn With Trisomy 21: A Case Report.
| Autor: | Cabanas CC; Pediatrics, Texas Tech University Health Sciences Center, Amarillo, USA., Falconi S; General Surgery, Texas Tech University Health Sciences Center, Lubbock, USA., Jones H; General Surgery, Texas Tech University Health Sciences Center, Lubbock, USA., Subhani M; Neonatology, Texas Tech University Health Sciences Center, Amarillo, USA., Adesanya OA; Neonatology, Texas Tech University Health Sciences Center, Amarillo, USA. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 May 16; Vol. 15 (5), pp. e39107. Date of Electronic Publication: 2023 May 16 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.39107 |
| Abstrakt: | Trisomy 21, or Down syndrome (DS), is neonates' most common chromosomal abnormality. In addition, children born with DS have an increased risk of congenital anomalies such as congenital heart defects, gastrointestinal abnormalities, and, rarely, cleft palate. Cleft lip and palate are among the most common congenital anomalies associated with many congenital syndromes; however, Trisomy 21 is the least common congenital anomaly associated with orofacial clefts. We present a case of cleft palate, duodenal stenosis, persistent pulmonary hypertension of the newborn, patent ductus arteriosus, and atrial septal defect in a newborn with classical clinical features of Down syndrome. This report discusses the uncommon presentation of trisomy 21 and concomitant cleft palate in a neonate, including its recognition and treatment, as no standard of care treatment exists. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Cabanas et al.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|