Obesity and female sexual dysfunctions: A systematic review of prevalence with meta-analysis.

Autor:	Ferrández Infante A; Coordinator of the Primary Care Physicians Spanish Society (SEMERGEN) Sexology Working Group, Guadarrama Continuity Care Center, 28440 Madrid, Spain. Electronic address: aferrandezinfante@gmail.com., Novella Arribas B; Grupo de Investigación 49, Instituto de Investigación del Hospital Universitario de La Princesa, Foundation for Biomedical Research and Innovation in Primary Care of the Community of Madrid (FIIBAP), 28006 Madrid, Spain., Khan KS; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain; Department of Preventive Medicine and Public Health, University of Granada, 18016 Granada, Spain., Zamora J; Head of the Clinical Biostatistics Unit, Hospital Ramón y Cajal, IRYCIS, 28034 Madrid, Spain; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain., Jurado López AR; Member of the Primary Care Physicians Spanish Society (SEMERGEN) Sexology Working Group, President of the European Institute of Sexology, 29602 Marbella, Spain., Fragoso Pasero M; Biostatistician, Grupo de Investigación 49, Instituto de Investigación del Hospital Universitario de La Princesa, Foundation for Biomedical Research and Innovation in Primary Care of the Community of Madrid (FIIBAP), 28006 Madrid, Spain., Suárez Fernández C; Head of the Internal Medicine Service of the Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Jazyk:	angličtina
Zdroj:	Semergen [Semergen] 2023 Oct; Vol. 49 (7), pp. 102022. Date of Electronic Publication: 2023 Jun 16.
DOI:	10.1016/j.semerg.2023.102022
Abstrakt:	Obesity represents a major global health challenge. Female sexual dysfunctions have a negative impact on quality of life and overall health balance. A higher rate of female sexual dysfunctions in obese women has been suggested. This systematic review summarized the literature on female sexual dysfunction prevalence in obese women. The review was registered (Open Science Framework OSF.IO/7CG95) and a literature search without language restrictions was conducted in PubMed, Embase and Web of Science, from January 1990 to December 2021. Cross-sectional and intervention studies were included, the latter if they provided female sexual dysfunction rate data in obese women prior to the intervention. For inclusion, studies should have used the female sexual function index or its simplified version. Study quality was assessed to evaluate if female sexual function index was properly applied using six items. Rates of female sexual dysfunctions examining for differences between obese vs class III obese and high vs low quality subgroups were summarized. Random effects meta-analysis was performed, calculating 95% confidence intervals (CI) and examining heterogeneity with I 2 statistic. Publication bias was evaluated with funnel plot. There were 15 relevant studies (1720 women participants in total with 153 obese and 1567 class III obese women). Of these, 8 (53.3%) studies complied with >4 quality items. Overall prevalence of female sexual dysfunctions was 62% (95% CI 55-68%; I 2 85.5%). Among obese women the prevalence was 69% (95% CI 55-80%; I 2 73.8%) vs 59% (95% CI 52-66%; I 2 87.5%) among those class III obese (subgroup difference p=0.15). Among high quality studies the prevalence was 54% (95% CI 50-60%; I 2 46.8%) vs 72% (95% CI 61-81%; I 2 88.0%) among low quality studies (subgroup difference p=0.002). There was no funnel asymmetry. We interpreted that the rate of sexual dysfunctions is high in obese and class III obese women. Obesity should be regarded as a risk factor for female sexual dysfunctions. (Copyright © 2023 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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