Low-intake dehydration prevalence in non-hospitalised older adults: Systematic review and meta-analysis.

Autor: Parkinson E; School of Health Sciences, University of East Anglia, Norwich, NR4 7TJ, United Kingdom. Electronic address: Ellice.parkinson@uea.ac.uk., Hooper L; Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, United Kingdom. Electronic address: L.hooper@uea.ac.uk., Fynn J; Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, United Kingdom. Electronic address: J.fynn@uea.ac.uk., Wilsher SH; Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, United Kingdom. Electronic address: Stephanie.Howard@uea.ac.uk., Oladosu T; Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, United Kingdom. Electronic address: titi.oladosu@doctors.org.uk., Poland F; School of Health Sciences, University of East Anglia, Norwich, NR4 7TJ, United Kingdom. Electronic address: F.poland@uea.ac.uk., Roberts S; The Centre for Research in Public Health and Community Care (CRIPACC), University of Hertfordshire, Hatfield, United Kingdom. Electronic address: s.roberts26@herts.ac.uk., Van Hout E; School of Health Sciences, University of East Anglia, Norwich, NR4 7TJ, United Kingdom. Electronic address: e.van-hout@uea.ac.uk., Bunn D; School of Health Sciences, University of East Anglia, Norwich, NR4 7TJ, United Kingdom. Electronic address: D.bunn@uea.ac.uk.
Jazyk: angličtina
Zdroj: Clinical nutrition (Edinburgh, Scotland) [Clin Nutr] 2023 Aug; Vol. 42 (8), pp. 1510-1520. Date of Electronic Publication: 2023 Jun 08.
DOI: 10.1016/j.clnu.2023.06.010
Abstrakt: Background & Aims: Low-intake dehydration amongst older people, caused by insufficient fluid intake, is associated with mortality, multiple long-term health conditions and hospitalisation. The prevalence of low-intake dehydration in older adults, and which groups are most at-risk, is unclear. We conducted a high-quality systematic review and meta-analysis, implementing an innovative methodology, to establish the prevalence of low-intake dehydration in older people (PROSPERO registration: CRD42021241252).
Method: We systematically searched Medline (Ovid), Cochrane CENTRAL, Embase (Ovid), CINAHL and Proquest from inception until April 2023 and Nutrition and Food Sciences until March 2021. We included studies that assessed hydration status for non-hospitalised participants aged ≥65 years, by directly-measured serum/plasma osmolality, calculated serum/plasma osmolarity and/or 24-h oral fluid intake. Inclusion, data extraction and risk of bias assessment was carried out independently in duplicate.
Results: From 11,077 titles and abstracts, we included 61 (22,398 participants), including 44 in quality-effects meta-analysis. Meta-analysis suggested that 24% (95% CI: 0.07, 0.46) of older people were dehydrated (assessed using directly-measured osmolality >300 mOsm/kg, the most reliable measure). Subgroup analyses indicated that both long-term care residents (34%, 95% CI: 0.09, 0.61) and community-dwelling older adults (19%, 95% CI: 0.00, 0.48) were highly likely to be dehydrated. Those with more pre-existing illnesses (37%, 95% CI: 0.14, 0.62) had higher low-intake dehydration prevalence than others (15%, 95% CI: 0.00, 0.43), and there was a non-significant suggestion that those with renal impairment (42%, 95% CI: 0.23, 0.61) were more likely to be dehydrated than others (23%, 95% CI: 0.03, 0.47), but there were no clear differences in prevalence by age, sex, functional, cognitive or diabetic status. GRADE quality of evidence was low as to the exact prevalence due to high levels of heterogeneity between studies.
Conclusion: Quality-effects meta-analysis estimated that a quarter of non-hospitalised older people were dehydrated. Widely varying prevalence rates in individual studies, from both long-term care and community groups, highlight that dehydration is preventable amongst older people.
Implications: One in every 4 older adults has low-intake dehydration. As dehydration is serious and prevalent, research is needed to better understand drinking behaviour and assess effectiveness of drinking interventions for older people.
Competing Interests: Conflicts of interest Ellice Parkinson: None. Lee Hooper: Hooper led some of the included prevalence studies. She was not involved in data extraction or risk of bias assessments on these studies, though did provide additional data where requested. Judith Fynn: None. Stephanie Howard Wilsher: None. Titilopemi Oladosu: None. Fiona Poland: None. Simone Roberts: None. Elien Van Hout: None. Diane Bunn: Bunn was involved in some of the included prevalence studies. She was not involved in data extraction or risk of bias assessments on these studies.
(Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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