Neurotrophic keratopathy following rhegmatogenous retinal detachment surgery.

Autor: Israilevich RN; Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA., Syed ZA; Cornea Service, Wills Eye Hospital, Philadelphia, PA., Xu D; Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA., Kaiser RS; Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA., Garg SJ; Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA., Spirn MJ; Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA., Mehta S; Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA., Gupta OP; Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA., Ho AC; Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA., Kuriyan AE; Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA., Yonekawa Y; Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA., Starr MR; Mid Atlantic Retina, Wills Eye Hospital, Philadelphia, PA; Department of Ophthalmology, Mayo Clinic, Rochester, MN. Electronic address: mstarr1724@gmail.com.
Jazyk: angličtina
Zdroj: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie [Can J Ophthalmol] 2024 Aug; Vol. 59 (4), pp. e321-e326. Date of Electronic Publication: 2023 Jun 14.
DOI: 10.1016/j.jcjo.2023.05.015
Abstrakt: Objective: To describe clinical characteristics and visual outcomes of eyes developing neurotrophic keratopathy (NK) following rhegmatogenous retinal detachment (RRD) repair.
Methods: All eyes with NK at Wills Eye Hospital following RRD repair from June 1, 2011, to December 1, 2020 were included. Patients with prior ocular procedures (other than cataract surgery), herpetic keratitis, and diabetes mellitus were excluded.
Results: During the study period, 241 patients were diagnosed with NK, and 8179 eyes underwent RRD surgery, giving a 9-year prevalence rate of 0.1% (95% CI, 0.1%-0.2%). Mean age was 53.4 ± 16.6 years during RRD repair and 56.5 ± 13.4 years during NK diagnosis. Mean time to NK diagnosis was 3.0 ± 5.6 years (range, 6 days to 18.8 years). Mean visual acuity before NK was 1.10 ± 0.56 logMAR (20/252 Snellen), and it was 1.01 ± 0.62 logMAR (20/205 Snellen) at final visit (p = 0.75). Six eyes (54.5%) developed NK <1 year following RRD surgery. Mean final visual acuity was 1.01 ± 0.53 logMAR (20/205 Snellen) in this group versus 1.01 ± 0.78 logMAR (20/205 Snellen) in the delayed NK group (p = 1.00).
Conclusions: NK may present acutely or up to several years following surgery, with severity of corneal defects ranging from stage 1 to stage 3 NK. Surgeons should be mindful of the potential for this rare complication following RRD repair.
(Copyright © 2023 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: