Aircraft noise and cardiovascular morbidity and mortality near Heathrow Airport: A case-crossover study.

Autor: Itzkowitz N; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; Department of Epidemiology, Columbia University Mailman School of Public Health, New York, USA., Gong X; Centre for Environmental Health and Sustainability, University of Leicester, Leicester, UK; National Institute for Health Research (NIHR) Health Protection Research Unit (HPRU) in Environmental Exposures and Health at the University of Leicester, UK., Atilola G; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; GOS Institute of Child Health, University College London, London, UK., Konstantinoudis G; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Adams K; Centre for Environmental Health and Sustainability, University of Leicester, Leicester, UK., Jephcote C; Centre for Environmental Health and Sustainability, University of Leicester, Leicester, UK., Gulliver J; Centre for Environmental Health and Sustainability, University of Leicester, Leicester, UK; National Institute for Health Research (NIHR) Health Protection Research Unit (HPRU) in Environmental Exposures and Health at the University of Leicester, UK., Hansell AL; Centre for Environmental Health and Sustainability, University of Leicester, Leicester, UK; National Institute for Health Research (NIHR) Health Protection Research Unit (HPRU) in Environmental Exposures and Health at the University of Leicester, UK., Blangiardo M; MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. Electronic address: m.blangiardo@imperial.ac.uk.
Jazyk: angličtina
Zdroj: Environment international [Environ Int] 2023 Jul; Vol. 177, pp. 108016. Date of Electronic Publication: 2023 Jun 03.
DOI: 10.1016/j.envint.2023.108016
Abstrakt: Aircraft noise causes annoyance and sleep disturbance and there is some evidence of associations between long-term exposures and cardiovascular disease (CVD). We investigated short-term associations between previous day aircraft noise and cardiovascular events in a population of 6.3 million residing near Heathrow Airport using a case-crossover design and exposure data for different times of day and night. We included all recorded hospitalisations (n = 442,442) and deaths (n = 49,443) in 2014-2018 due to CVD. Conditional logistic regression was used to estimate the ORs and adjusted for NO 2 concentration, temperature, and holidays. We estimated an increase in risk for 10 dB increment in noise during the previous evening (L eve OR = 1.007, 95% CI 0.999-1.015), particularly from 22:00-23:00 h (OR = 1.007, 95% CI 1.000-1.013), and the early morning hours 04:30-06:00 h (OR = 1.012, 95% CI 1.002-1.021) for all CVD admissions, but no significant associations with day-time noise. There was effect modification by age-sex, ethnicity, deprivation, and season, and some suggestion that high noise variability at night was associated with higher risks. Our findings are consistent with proposed mechanisms for short-term impacts of aircraft noise at night on CVD from experimental studies, including sleep disturbance, increases in blood pressure and stress hormone levels and impaired endothelial function.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: