USE OF A POINT OF CARE TEST TO DETERMINE THE PREVALENCE OF ANTIBODIES TO TOXOPLASMA GONDII IN BLACK BEARS FROM NORTH CAROLINA AND PENNSYLVANIA.

Autor:	Strules J; Department of Forestry and Environmental Resources, Fisheries, Wildlife, and Conservation Biology, North Carolina State University, Raleigh, North Carolina 27606., Dawant T; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996., Riese K; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996., Gerhold R; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996., Brown J; Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, Pennsylvania 16802., Olfenbuttel C; North Carolina Wildlife Resources Commission, Raleigh, North Carolina 27699., DePerno CS; Department of Forestry and Environmental Resources, Fisheries, Wildlife, and Conservation Biology, North Carolina State University, Raleigh, North Carolina 27606., Hunt BJ; Department of Computer Sciences, Engineering and Mathematics, College of Science, Technology, Engineering and Mathematics, Johnson C. Smith University, Charlotte, North Carolina 28216., von Dohlen AR; Department of Natural and Behavioral Sciences, College of Science, Technology, Engineering and Mathematics, Johnson C. Smith University, Charlotte, North Carolina 28216.
Jazyk:	angličtina
Zdroj:	The Journal of parasitology [J Parasitol] 2023 May 01; Vol. 109 (3), pp. 221-224.
DOI:	10.1645/22-72
Abstrakt:	Toxoplasma gondii is an important protozoan parasite of humans and animals throughout the world. Black bears are among the animals with the highest seroprevalence of T. gondii in the United States. A rapid point of care (POC) test is commercially available to detect antibodies to T. gondii in humans. We evaluated the utility of the POC test to detect anti-T. gondii antibodies in 100 wild black bears from North Carolina (n = 50) and Pennsylvania (n = 50). In a blind study, sera were tested by the POC test, and results were compared to the modified agglutination test (MAT). Overall, anti-T. gondii antibodies were detected in 76% (76/100) black bears by both MAT and POC tests. One false positive and one false negative result in the POC test were obtained in bears from Pennsylvania. The sensitivity and specificity of the POC test were both 99% when compared to the MAT. Results from our study indicate the POC test could be a useful screening tool for serological surveillance of T. gondii in black bears. (© American Society of Parasitologists 2023.)
Databáze:	MEDLINE
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