| Abstrakt: |
The effects of adrenergic agonists and glucagon on respiration and cytosolic free Ca2+, measured with quin2, in female rat hepatocytes have been compared. In the presence of lactate, all three agonists caused a permanent stimulation of respiration. However, unlike phenylephrine, glucagon induced only a transient increase in cytosolic free Ca2+, and isoprenaline caused no detectable change. Mechanisms other than Ca2+ for respiratory stimulation by cAMP-linked agonists in liver are indicated. |
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