Role of bioaerosol in virus transmission and material-based countermeasures.

Autor: Joseph J; Center for Nanomedicine, Department of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital Boston Massachusetts USA.; Harvard Medical School Boston Massachusetts USA., Baby HM; Center for Nanomedicine, Department of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital Boston Massachusetts USA., Zhao S; Center for Nanomedicine, Department of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital Boston Massachusetts USA., Li XL; Center for Nanomedicine, Department of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital Boston Massachusetts USA., Cheung KC; Center for Nanomedicine, Department of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital Boston Massachusetts USA., Swain K; Center for Nanomedicine, Department of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital Boston Massachusetts USA., Agus E; Center for Nanomedicine, Department of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital Boston Massachusetts USA., Ranganathan S; Center for Nanomedicine, Department of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital Boston Massachusetts USA., Gao J; Center for Nanomedicine, Department of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital Boston Massachusetts USA.; Harvard Medical School Boston Massachusetts USA., Luo JN; Harvard Medical School Boston Massachusetts USA.; Department of Surgery Brigham and Women's Hospital Boston Massachusetts USA., Joshi N; Center for Nanomedicine, Department of Anesthesiology Perioperative and Pain Medicine, Brigham and Women's Hospital Boston Massachusetts USA.; Harvard Medical School Boston Massachusetts USA.
Jazyk: angličtina
Zdroj: Exploration (Beijing, China) [Exploration (Beijing)] 2022 May 23; Vol. 2 (6), pp. 20210038. Date of Electronic Publication: 2022 May 23 (Print Publication: 2022).
DOI: 10.1002/EXP.20210038
Abstrakt: Respiratory pathogens transmit primarily through particles such as droplets and aerosols. Although often overlooked, the resuspension of settled droplets is also a key facilitator of disease transmission. In this review, we discuss the three main mechanisms of aerosol generation: direct generation such as coughing and sneezing, indirect generation such as medical procedures, and resuspension of settled droplets and aerosols. The size of particles and environmental factors influence their airborne lifetime and ability to cause infection. Specifically, humidity and temperature are key factors controlling the evaporation of suspended droplets, consequently affecting the duration in which particles remain airborne. We also suggest material-based approaches for effective prevention of disease transmission. These approaches include electrostatically charged virucidal agents and surface coatings, which have been shown to be highly effective in deactivating and reducing resuspension of pathogen-laden aerosols.
Competing Interests: The authors declare no conflict of interest.
(© 2022 The Authors. Exploration published by Henan University and John Wiley & Sons Australia, Ltd.)
Databáze: MEDLINE
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