Systemic Diseases and Heart Block.
| Autor: | Sabzwari SRA; University of Colorado Anschutz Medical Campus, 12631 East 17th Avenue, Mail Stop B130, Aurora, CO 80045, USA., Tzou WS; Cardiac Electrophysiology, University of Colorado Anschutz Medical Campus, 12401 E 17th Avenue, MS B-136, Aurora, CO 80045, USA. Electronic address: Wendy.Tzou@cuanschutz.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Cardiology clinics [Cardiol Clin] 2023 Aug; Vol. 41 (3), pp. 429-448. |
| DOI: | 10.1016/j.ccl.2023.03.008 |
| Abstrakt: | Systemic diseases can cause heart block owing to the involvement of the myocardium and thereby the conduction system. Younger patients (<60) with heart block should be evaluated for an underlying systemic disease. These disorders are classified into infiltrative, rheumatologic, endocrine, and hereditary neuromuscular degenerative diseases. Cardiac amyloidosis owing to amyloid fibrils and cardiac sarcoidosis owing to noncaseating granulomas can infiltrate the conduction system leading to heart block. Accelerated atherosclerosis, vasculitis, myocarditis, and interstitial inflammation contribute to heart block in rheumatologic disorders. Myotonic, Becker, and Duchenne muscular dystrophies are neuromuscular diseases involving the myocardium skeletal muscles and can cause heart block. Competing Interests: Disclosure Dr W.Z. Tzou is a consultant for or has received speaker honoraria, or research funding from Abbott, American Heart Association, Biosense Webster, Biotronik, Boston Scientific, and Medtronic. Dr S.R.A. Sabzwari has no relevant disclosures. (Copyright © 2023 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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