CATCH-UP vaccines: protocol for a randomized controlled trial using the multiphase optimization strategy (MOST) framework to evaluate education interventions to increase COVID-19 vaccine uptake in Oklahoma.

Autor: Janitz AE; University of Oklahoma Health Sciences Center, 801 NE 13th St., CHB 309, Oklahoma City, OK, 73104, USA. Amanda-Janitz@ouhsc.edu., Neil JM; University of Oklahoma Health Sciences Center, 801 NE 13th St., CHB 309, Oklahoma City, OK, 73104, USA., Bray LA; University of Oklahoma Norman Campus, 5 Partners Place, 201 Stephenson Parkway, Suite 4100, Norman, OK, 73072, USA., Jervis LL; University of Oklahoma Norman Campus, 5 Partners Place, 201 Stephenson Parkway, Suite 4100, Norman, OK, 73072, USA., Ross L; Public Health Institute of Oklahoma, P.O. Box 60926, Oklahoma City, OK, 73146, USA., Campbell JE; University of Oklahoma Health Sciences Center, 801 NE 13th St., CHB 309, Oklahoma City, OK, 73104, USA., Doescher MP; University of Oklahoma Health Sciences Center, 801 NE 13th St., CHB 309, Oklahoma City, OK, 73104, USA., Spicer PG; University of Oklahoma Norman Campus, 5 Partners Place, 201 Stephenson Parkway, Suite 4100, Norman, OK, 73072, USA., Williams ML; University of Oklahoma Health Sciences Center, 801 NE 13th St., CHB 309, Oklahoma City, OK, 73104, USA., Lopez AK; University of Oklahoma Health Sciences Center, 801 NE 13th St., CHB 309, Oklahoma City, OK, 73104, USA., Uribe-Frias CA; University of Oklahoma Health Sciences Center, 801 NE 13th St., CHB 309, Oklahoma City, OK, 73104, USA., Chen S; University of Oklahoma Health Sciences Center, 801 NE 13th St., CHB 309, Oklahoma City, OK, 73104, USA., James JA; Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, 73104, USA., VanWagoner TM; University of Oklahoma Health Sciences Center, 801 NE 13th St., CHB 309, Oklahoma City, OK, 73104, USA.
Jazyk: angličtina
Zdroj: BMC public health [BMC Public Health] 2023 Jun 14; Vol. 23 (1), pp. 1146. Date of Electronic Publication: 2023 Jun 14.
DOI: 10.1186/s12889-023-16077-w
Abstrakt: Background: Oklahoma's cumulative COVID-19 incidence is higher in rural than urban counties and higher than the overall US incidence. Furthermore, fewer Oklahomans have received at least one COVID-19 vaccine compared to the US average. Our goal is to conduct a randomized controlled trial using the multiphase optimization strategy (MOST) to test multiple educational interventions to improve uptake of COVID-19 vaccination among underserved populations in Oklahoma.
Methods: Our study uses the preparation and optimization phases of the MOST framework. We conduct focus groups among community partners and community members previously involved in hosting COVID-19 testing events to inform intervention design (preparation). In a randomized clinical trial, we test three interventions to improve vaccination uptake: (1) process improvement (text messages); (2) barrier elicitation and reduction (electronic survey with tailored questions/prompts); and (2) teachable moment messaging (motivational interviewing) in a three-factor fully crossed factorial design (optimization).
Discussion: Because of Oklahoma's higher COVID-19 impact and lower vaccine uptake, identifying community-driven interventions is critical to address vaccine hesitancy. The MOST framework provides an innovative and timely opportunity to efficiently evaluate multiple educational interventions in a single study.
Trial Registration: ClinicalTrials.gov: NCT05236270, First Posted: February 11, 2022, Last Update Posted: August 31, 2022.
(© 2023. The Author(s).)
Databáze: MEDLINE
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