Epidemiology and outcome of an acute kidney injuries in the polytrauma victims admitted at the apex trauma center in Dubai.

Autor: Wankhade BS; Department of Surgical Intensive Care Medicine, Rashid Hospital, Oud Metha, Dubai, UAE.; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE., Alrais ZF; Department of Surgical Intensive Care Medicine, Rashid Hospital, Oud Metha, Dubai, UAE.; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE., Alrais GZ; Dubai Medical College, Dubai, UAE., Hadi AMA; Department of Surgical Intensive Care Medicine, Rashid Hospital, Oud Metha, Dubai, UAE., Naidu GAK; Department of Surgical Intensive Care Medicine, Rashid Hospital, Oud Metha, Dubai, UAE., Abbas MS; Department of Surgical Intensive Care Medicine, Rashid Hospital, Oud Metha, Dubai, UAE., Kheir ATYA; Department of Surgical Intensive Care Medicine, Rashid Hospital, Oud Metha, Dubai, UAE., Hadad H; Emergency Department, Emirates Hospital, Jumeirah, Dubai, UAE., Sharma S; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE., Sait M; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE.
Jazyk: angličtina
Zdroj: Acute and critical care [Acute Crit Care] 2023 May; Vol. 38 (2), pp. 217-225. Date of Electronic Publication: 2023 May 25.
DOI: 10.4266/acc.2023.00388
Abstrakt: Background: Polytrauma from road accidents is a common cause of hospital admissions and deaths, frequently leading to acute kidney injury (AKI) and impacting patient outcomes.
Methods: This retrospective, single-center study included polytrauma victims with an Injury Severity Score (ISS) >25 at a tertiary healthcare center in Dubai.
Results: The incidence of AKI in polytrauma victims is 30.5%, associated with higher Carlson comorbidity index (P=0.021) and ISS (P=0.001). Logistic regression shows a significant relationship between ISS and AKI (odds ratio [OR], 1.191; 95% confidence interval [CI], 1.150-1.233; P<0.05). The main causes of trauma-induced AKI are hemorrhagic shock (P=0.001), need for massive transfusion (P<0.001), rhabdomyolysis (P=0.001), and abdominal compartment syndrome (ACS; P<0.001). On multivariate logistic regression AKI can be predicated by higher ISS (OR, 1.08; 95% CI, 1.00-1.17; P=0.05) and low mixed venous oxygen saturation (OR, 1.13; 95% CI, 1.05-1.22; P<0.001). The development of AKI after polytrauma increases length of stay (LOS)-hospital (P=0.006), LOS-intensive care unit (ICU; P=0.003), need for mechanical ventilation (MV) (P<0.001), ventilator days (P=0.001), and mortality (P<0.001).
Conclusions: After polytrauma, the occurrence of AKI leads to prolonged hospital and ICU stays, increased need for mechanical ventilation, more ventilator days, and a higher mortality rate. AKI could significantly impact their prognosis.
Databáze: MEDLINE
Externí odkaz: