Diagnostic challenge: primary leptomeningeal melanoma with melanomatosis, illustrative case report.

Autor: El Ouazzani H; Department of Pathology HSR, Ibn Sina University Hospital Center in Rabat, Morocco.; Mohammed V University in Rabat, Morocco., Oudghiri MY; Mohammed V University in Rabat, Morocco.; Department of Neurosurgery HSR, Ibn Sina University Hospital Center in Rabat, Morocco., Abbas S; Mohammed V University in Rabat, Morocco.; Department of Neurosurgery HSR, Ibn Sina University Hospital Center in Rabat, Morocco., Regragui A; Mohammed V University in Rabat, Morocco.; Department of Neurosurgery HSR, Ibn Sina University Hospital Center in Rabat, Morocco., Elouahabi A; Mohammed V University in Rabat, Morocco.; Department of Neurosurgery HSR, Ibn Sina University Hospital Center in Rabat, Morocco., Zouaidia F; Mohammed V University in Rabat, Morocco.; Department of Pathology Ibn Sina, Ibn Sina University Hospital Center in Rabat, Morocco., Cherradi N; Department of Pathology HSR, Ibn Sina University Hospital Center in Rabat, Morocco.; Mohammed V University in Rabat, Morocco.
Jazyk: angličtina
Zdroj: Journal of surgical case reports [J Surg Case Rep] 2023 Jun 12; Vol. 2023 (6), pp. rjad323. Date of Electronic Publication: 2023 Jun 12 (Print Publication: 2023).
DOI: 10.1093/jscr/rjad323
Abstrakt: Primary leptomeningeal melanoma is an extremely rare type of intracranial melanoma. It cannot be reliably distinguished from metastatic melanoma on neuroimaging and histopathological characteristics alone; its diagnosis is established only after exclusion of secondary metastatic disease from a cutaneous, mucosal or retinal primary. Prognosis is poor, partly due to its high rate of misdiagnosis. Herein, we report a case of a primary meningeal melanoma of the skull base with melanomatosis, in a 31-year-old man, mimicking meningioma. Our aim is to highlight the diagnostic pitfalls and to discuss the histopathological differential diagnoses, especially with other pigmented lesions of central nervous system.
Competing Interests: None declared.
(Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023.)
Databáze: MEDLINE
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