Marital status impact on the outcomes of patients admitted for acute decompensation of heart failure: A retrospective, single-center, analysis.

Autor: Marcus G; Cardiology, Shamir Medical Center, Be'er-Yaakov, Israel.; Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv, Israel., Kofman N; Cardiology, Shamir Medical Center, Be'er-Yaakov, Israel.; Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv, Israel., Maymon SL; Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv, Israel., Asher E; The Jesselson Integrated Heart Center, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University, Jerusalem, Israel., Loberman D; Cape Cod Hospital, Brigham and Women's Hospital, Harvard Medical School, Division of Cardiac Surgery, Boston, Massachusetts, USA., Pereg D; Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv, Israel.; Cardiology Department, Meir Medical Center, Kfar-Saba, Israel., Fuchs S; Cardiology, Shamir Medical Center, Be'er-Yaakov, Israel.; Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv, Israel., Minha S; Cardiology, Shamir Medical Center, Be'er-Yaakov, Israel.; Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv, Israel.
Jazyk: angličtina
Zdroj: Clinical cardiology [Clin Cardiol] 2023 Aug; Vol. 46 (8), pp. 914-921. Date of Electronic Publication: 2023 Jun 12.
DOI: 10.1002/clc.24053
Abstrakt: Background: Conflicting evidence exists regarding the association between marital status and outcomes in patients with heart failure (HF). Further, it is not clear whether type of unmarried status (never married, divorced, or widowed) disparities exist in this context.
Hypothesis: We hypothesized that marital status will be associated with better outcomes in patients with HF.
Methods: This single-center retrospective study utilized a cohort of 7457 patients admitted with acute decompensated HF (ADHF) between 2007 and 2017. We compared baseline characteristics, clinical indices, and outcomes of these patients grouped by their marital status. Cox regression analysis was used to explore the independency of the association between marital status and long-term outcomes.
Results: Married patients accounted for 52% of the population while 37%, 9%, and 2% were widowed, divorced, and never married, respectively. Unmarried patients were older (79.8 ± 11.5 vs. 74.8 ± 11.1 years; p < 0.001), more frequently women (71.4% vs. 33.2%; p < 0.001), and less likely to have traditional cardiovascular comorbidities. Compared with married patients, all-cause mortality incidence was higher in unmarried patients at 30 days (14.7% vs. 11.1%, p < 0.001), 1 year, and 5 years (72.9% vs. 68.4%, p < 0.001). Nonadjusted Kaplan-Meier estimates for 5-year all-cause mortality by sex, demonstrated the best prognosis for married women, and by marital status in unmarried patients, the best prognosis was demonstrated in divorced patients while the worst was recorded in widowed patients. After adjustment for covariates, marital status was not found to be independently associated with ADHF outcomes.
Conclusions: Marital status is not independently associated with outcomes of patients admitted for ADHF. Efforts for outcomes improvement should focus on other, more traditional risk factors.
(© 2023 The Authors. Clinical Cardiology published by Wiley Periodicals LLC.)
Databáze: MEDLINE
Externí odkaz: