Ethanolic extract of Etlingera elatior flower exhibits anthelmintic properties to Fasciola gigantica in vitro .
| Autor: | Wulandari AR; Department of Animal Science, Faculty of Agriculture, Universitas Sebelas Maret, Surakarta, Indonesia., Nurlaelasari A; Department of Animal Science, Faculty of Agriculture, Universitas Sebelas Maret, Surakarta, Indonesia., Nugroho HA; Reseach Center for Applied Zoology, National Research and Innovation Agency, Jakarta Pusat, Indonesia., Cahyadi M; Department of Animal Science, Faculty of Agriculture, Universitas Sebelas Maret, Surakarta, Indonesia., Kurniawan W; Department of Animal Production, Agency of Livestock and Fishery Services, Boyolali District, Central Java, Indonesia., Hamid PH; Department of Animal Science, Faculty of Agriculture, Universitas Sebelas Maret, Surakarta, Indonesia. |
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| Jazyk: | angličtina |
| Zdroj: | Open veterinary journal [Open Vet J] 2023 May; Vol. 13 (5), pp. 576-587. Date of Electronic Publication: 2023 May 11. |
| DOI: | 10.5455/OVJ.2023.v13.i5.10 |
| Abstrakt: | Background: Fasciolosis is a parasitic disease affecting the hepatobiliary system of livestock worldwide. The control of the fluke is important to be performed in endemic regions. Aim: This study aims to evaluate the effect of Etlingera elatior ethanolic extract on egg and adult stadia of Fasciola gigantica . Methods: Fasciola gigantica in different stages were incubated with E. elatior ethanolic extract in different concentrations and time points. Results: The number of developed eggs with different concentrations of 1.25%, 2.5%, and 5% was significantly decreased by 36.67%, 56.67%, and 56.67% on day 11 post-incubation, which showed an ovicidal effect of the herb. The developed eggs on day 14, which were represented by hatched larvae, were also decreased by 70%, 50%, and 13.33%, respectively. Significant flukicidal effects were observed in the incubation time of 80 minutes for the concentration of 20% ( p = 0.007) and 640 minutes for 10% concentration ( p = 0.003). Surface microscopy of adult F. gigantica showed damaged skin and spina with the erosion of the inner membrane and detached syncytium from the tegument. Conclusion: Overall, the results indicate that E. elatior has a promising anthelmintic property against F. gigantica in both ova and adult stages. Competing Interests: The authors declare that there is no conflict of interest |
| Databáze: | MEDLINE |
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