Clinical and Demographic Characteristics of Immigrant and Local Multiple Sclerosis Patients in Turkey.

Autor: Balcı BP; Health Sciences University, Hamidiye Faculty of Medicine, Department of Neurology, İstanbul, Turkey.; Health Sciences University Haseki Training and Research Hospital Neurology Clinic, İstanbul, Turkey., Bakırcıoğlu Duman E; Health Sciences University Haseki Training and Research Hospital Neurology Clinic, İstanbul, Turkey., Tunç C; Health Sciences University Haseki Training and Research Hospital Neurology Clinic, İstanbul, Turkey., Tüzün BB; Health Sciences University, Hamidiye Faculty of Medicine, Department of Neurology, İstanbul, Turkey., Çokar Ö; Health Sciences University, Hamidiye Faculty of Medicine, Department of Neurology, İstanbul, Turkey.
Jazyk: angličtina
Zdroj: Noro psikiyatri arsivi [Noro Psikiyatr Ars] 2022 Dec 27; Vol. 60 (2), pp. 104-109. Date of Electronic Publication: 2022 Dec 27 (Print Publication: 2023).
DOI: 10.29399/npa.28078
Abstrakt: Introduction: Increasing migration, due to wars, is one of the environmental factors in the etiology of multiple sclerosis. This study aims to compare demographic and clinical features of immigrant and local MS patients, as well as relapses during pregnancy and postpartum in female patients.
Method: Immigrant (Group 1) and local (Group 2) MS patients were evaluated between January 2019 - September 2020 retrospectively. Below-mentioned data of two groups were recorded and compared: i) demographic data, ii) cerebrospinal fluid (CSF) and magnetic resonance imaging (MRI) findings, iii) MS subtypes, iv) expanded disability status scores (EDSS), v) the time between first two relapses, vi) comorbidities, vii) treatment, viii) age of migration and country of origin, ix) pregnancy, x) relapse during pregnancy, xi) birth number, xii) breastfeeding, xiii) postpartum relapses.
Results: Both of the groups were composed of 34 MS patients (in total n=68). Gender distribution, mean age, MS subtypes, the time between first two relapses, disease duration, EDSS, CSF findings and comorbidities were similar between groups. Symptom of onset was predominantly sensory in both groups. Local patients had more cervical lesions and higher lesion load (p=0.003, p=0.006). 20.6% of migrant MS patients were untreated, all local patients were on treatment. Rates of injection and infusion therapies were similar, the rate of receiving oral therapy was higher in the second group. Clinical features and fertility status of female patients were similar.
Conclusion: According to the study no differences were preseentpresent between immigrant and local MS patients except for MRI lesion load and treatment parameters. The language barrier and irregular follow-ups were the major problems in treatment management.
Competing Interests: Conflict of Interest: The authors declared that there is no conflict of interest.
(Copyright: © 2023 Turkish Neuropsychiatric Society.)
Databáze: MEDLINE
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