Optimisation and implementation of QuEChERS-based sample preparation for identification and semi-quantification of 694 targeted contaminants in honey, jam, jelly, and syrup by UHPLC-Q/ToF high-resolution mass spectrometry.

Autor: Makni Y; ANSES, Laboratory for Food Safety, F-94701 Maisons-Alfort, France., Diallo T; ANSES, Laboratory for Food Safety, F-94701 Maisons-Alfort, France; Littoral Environnement et Sociétés (LIENSs), UMR 7266, CNRS-Université de La Rochelle, 2 rue Olympe de Gouges, F-17042 La Rochelle Cedex 01, France., Areskoug F; Man-Technology-Environment (MTM) Research Centre, School of Science and Technology, Örebro University, SE-701 82 Örebro, Sweden., Guérin T; ANSES, Strategy and Programmes Department, F-94701 Maisons-Alfort, France., Parinet J; ANSES, Laboratory for Food Safety, F-94701 Maisons-Alfort, France. Electronic address: julien.parinet@anses.fr.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2023 Nov 01; Vol. 425, pp. 136448. Date of Electronic Publication: 2023 May 24.
DOI: 10.1016/j.foodchem.2023.136448
Abstrakt: A screening and semi-quantitative method was developed for the analysis of 694 various contaminants in honey, jam, jelly and syrup samples by ultrahigh-performance liquid chromatography and quadrupole time-of-flight mass spectrometry. Sample preparation, which was optimised using split factorial design, was based on acetate-buffered version of QuEChERS, followed by a clean-up step and a concentration step to enhance sensitivity of analytes. The method was validated according to SANTE/11312/2021 guidelines. The screening detection and limits of identification were established as being less than or equal to 0.05 mg.kg -1 for 89% and 74% of the contaminants, respectively. The validated screening method was applied to 50 concentrated sugary products. Overall, 46% of the samples were positive to pesticide residues. Most of the positive samples (78%) contained mixtures of pesticide residues. Three time-and-cost saving convenient strategies suitable for high-throughput analysis were proposed for the targeted semi-quantification of the previously contaminants identified in samples.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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