Hydrophilic polymer embolism identified in brain tumor specimens following Wada testing: A report of 2 cases.

Autor: Goodwill VS; Department of Pathology, University of California, San Diego United States., Brandel MG; Department of Neurosurgery, University of California, San Diego United States., Steinberg JA; Department of Neurosurgery, University of California, San Diego United States., Beaumont TL; Department of Neurosurgery, University of California, San Diego United States., Hansen LA; Department of Pathology, University of California, San Diego United States.
Jazyk: angličtina
Zdroj: Free neuropathology [Free Neuropathol] 2021 Sep 02; Vol. 2. Date of Electronic Publication: 2021 Sep 02 (Print Publication: 2021).
DOI: 10.17879/freeneuropathology-2021-3457
Abstrakt: Hydrophilic polymers are commonly used as coatings on intravascular medical devices. As intravascular procedures continue to increase in frequency, the risk of embolization of this material throughout the body has become evident. These emboli may be discovered incidentally but can result in serious complications including death. Here, we report the first two cases of hydrophilic polymer embolism (HPE) identified on brain tumor resection following Wada testing. One patient experienced multifocal vascular complications and diffuse cerebral edema, while the other had an uneventful postoperative course. Wada testing is frequently performed during preoperative planning prior to epilepsy surgery or the resection of tumors in eloquent brain regions. These cases demonstrate the need for increased recognition of this histologic finding to enable further correlation with clinical outcomes.
Databáze: MEDLINE