| Autor: |
Vien LT; Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Caugiay, Hanoi 10072, Vietnam., Hanh TTH; Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Caugiay, Hanoi 10072, Vietnam., Quang TH; Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Caugiay, Hanoi 10072, Vietnam., Thanh NV; Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Caugiay, Hanoi 10072, Vietnam., Cuong NX; Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Caugiay, Hanoi 10072, Vietnam., Nam NH; Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Caugiay, Hanoi 10072, Vietnam., Do Cong T; Institute of Marine Environment and Resources (IMER), VAST, Haiphong 18000, Vietnam., Kiem PV; Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology (VAST), Caugiay, Hanoi 10072, Vietnam. |
| Abstrakt: |
Five asterosaponins ( 1 - 5 ), including one new compound named protonodososide ( 1 ), were isolated from the methanol extract of the starfish Protoreaster nodosus , after subjecting to various chromatographic separations. The structural elucidation was confirmed by careful analysis of the 1D, 2D NMR, and HR ESI QTOF mass spectra. The cytotoxicity of isolated compounds was evaluated on five human cancer cell lines including HepG2, KB, MCF7, LNCaP, and SK-Mel2. |
