The C3 conundrum.

Autor: Lean M; Nephrology and Transplantation Unit, John Hunter Hospital, Newcastle, New South Wales, Australia., Chacko B; Nephrology and Transplantation Unit, John Hunter Hospital, Newcastle, New South Wales, Australia.; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.
Jazyk: angličtina
Zdroj: Internal medicine journal [Intern Med J] 2023 Jun; Vol. 53 (6), pp. 1065-1069. Date of Electronic Publication: 2023 Jun 06.
DOI: 10.1111/imj.16111
Abstrakt: A 62-year-old man with nephritic syndrome underwent a kidney biopsy which revealed a C3 dominant pattern on immunofluorescence. A diagnosis of C3 glomerulopathy (C3G) was suspected. However, a recent skin infection and high levels of anti-streptococcal antibodies were indicative of post-infectious glomerulonephritis (PIGN). This paper compares PIGN and C3G and describes an atypical form of PIGN with alternative complement pathway dysregulation.
(© 2023 The Authors. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.)
Databáze: MEDLINE
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