Clinical outcomes of obstructive colorectal cancer patients during the coronavirus disease 2019 pandemic.

Autor:	Kulle CB; Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, İstanbul-Türkiye., Sengun B; Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, İstanbul-Türkiye., Gok AFK; Department of Surgery, Khoja Akhmet Yassawi International Kazakh-Turkish University School of Medicine, Kazakhstan., Ozgur I; Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, İstanbul-Türkiye., Bayraktar A; Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, İstanbul-Türkiye., Ertekin C; Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, İstanbul-Türkiye., Deniz AB; Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, İstanbul-Türkiye., Keskin M; Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, İstanbul-Türkiye.
Jazyk:	angličtina
Zdroj:	Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES [Ulus Travma Acil Cerrahi Derg] 2023 Jun; Vol. 29 (6), pp. 663-668.
DOI:	10.14744/tjtes.2023.44524
Abstrakt:	Background: The coronavirus disease 2019 (COVID-19) pandemic has affected all aspects of clinical care including diagnosis and treatment of colorectal cancers (CRCs) globally, including in Türkiye. During the initial peak of the pandemic, elective surgeries and outpatient clinics were restricted in addition to the government-imposed lockdown, resulting in a decrease in the number of colonoscopies being performed and patients admitted to inpatient wards for treatment of CRCs. In this study, we aimed to investigate whether the pandemic has affected presentation characteristics and outcomes of obstructive colorectal cancer in this period. Methods: This is a single-center, retrospective cohort study based on all CRC adenocarcinoma patients that underwent surgical resection in a high-volume tertiary referral center in Istanbul, Türkiye. Patients were divided into two groups before and after 15 months of identification of 'patient-zero' in Türkiye (March 18, 2020). Patient demographics, initial presentation characteristics, clin-ical outcomes, and pathological cancer stages were compared. Results: Overall, 215 patients underwent resection for CRC adenocarcinoma during 30 months (COVID era: 107, pre-COVID era: 108). Patient characteristics, tumor location, and clinical staging were comparable between two groups. During the COVID period, the number of obstructive CRCs (P<0.01) and emergency presentations (P<0.01) increased significantly compared to the respective pre-COVID period. However, there were no differences between 30-day morbidity, mortality, and pathological outcomes (P>0.05). Conclusion: Although the results of our study indicate a significant increase in emergency presentation and a decrease in elective admissions of CRCs during the pandemic, patients treated during the COVID period were not at a significant disadvantage in terms of post-operative outcomes. Further efforts should be made to decrease risks related to an emergency presentation of CRCs for future adverse events.
Databáze:	MEDLINE
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