Production and separation of positron emitters for hadron therapy at FRS-Cave M.

Autor: Haettner E; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Geissel H; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany.; II. Physikalisches Institut, Justus-Liebig-Universität, 35392, Gieβen, Germany., Franczak B; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Kostyleva D; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Purushothaman S; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Tanaka YK; RIKEN Cluster for Pioneering Research, RIKEN, 351-0198, Saitama, Japan., Amjad F; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Boscolo D; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Dickel T; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany.; II. Physikalisches Institut, Justus-Liebig-Universität, 35392, Gieβen, Germany., Graeff C; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Hessler C; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Hornung C; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Kazantseva E; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Kuzminchuk N; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Morrissey D; Department of Chemistry and NSCL, Michigan State University, 48824, East Lansing, USA., Mukha I; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Pietri S; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Rocco E; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Roy P; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Roesch H; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Schuy C; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Schütt P; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Weber U; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Weick H; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Zhao J; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany., Durante M; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany.; Institut für Physik Kondensierter Materie, Technische Universität Darmstadt, 64289, Darmstadt, Germany., Parodi K; Faculty of Physics, Department of Medical Physics, Ludwig-Maximilians-Universität München, 85748, München, Germany., Scheidenberger C; GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291, Darmstadt, Germany.; II. Physikalisches Institut, Justus-Liebig-Universität, 35392, Gieβen, Germany.; Helmholtz Research Academy Hesse for FAIR (HFHF), GSI Helmholtz Center for Heavy Ion Research, Campus Gieβen, 35392, Gieβen, Germany.
Jazyk: angličtina
Zdroj: Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms [Nucl Instrum Methods Phys Res B] 2023 Aug; Vol. 541, pp. 114-116. Date of Electronic Publication: 2023 May 19.
DOI: 10.1016/j.nimb.2023.04.026
Abstrakt: The FRagment Separator FRS at GSI is a versatile spectrometer and separator for experiments with relativistic in-flight separated short-lived exotic beams. One branch of the FRS is connected to the target hall where the bio-medical cave (Cave M) is located. Recently a joint activity between the experimental groups of the FRS and the biophysics at the GSI and Department of physics at LMU was started to perform biomedical experiments relevant for hadron therapy with positron emitting carbon and oxygen beams. This paper presents the new ion-optical mode and commissioning results of the FRS-Cave M branch where positron emitting 15 O-ions were provided to the medical cave for the first time. An overall conversion efficiency of 2.9±0.2×10 -4 15 O fragments per primary 16 O ion accelerated in the synchrotron SIS18 was reached.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Databáze: MEDLINE
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