Schizophrenia in autistic people with intellectual disabilities: Symptom manifestations and identification.

Autor: Bakken TL; Oslo University Hospital, Oslo Metropolitan University, Oslo, Norway., Kildahl AN; Oslo University Hospital, Oslo, Norway., Ludvigsen LB; Vestre Viken Hospital Trust, Gjettum, Norway., Bjørgen TG; St. Olavs University Hospital, Norwegian University of Science and Technology, Trondheim, Norway., Dalhaug C; Oslo University Hospital, Oslo, Norway., Hellerud JMA; Oslo University Hospital, Oslo, Norway., Hove O; Helse Fonna Hospital Trust, Haugesund, Norway., Solheim-Inderberg AM; Oslo University Hospital, Oslo, Norway., Karlsen K; Oslo University Hospital, Oslo, Norway., Helverschou SB; Oslo University Hospital, Oslo, Norway.
Jazyk: angličtina
Zdroj: Journal of applied research in intellectual disabilities : JARID [J Appl Res Intellect Disabil] 2023 Sep; Vol. 36 (5), pp. 1076-1091. Date of Electronic Publication: 2023 Jun 02.
DOI: 10.1111/jar.13127
Abstrakt: Background: The assessment of schizophrenia in autistic people with intellectual disabilities is challenging. This study aimed to explore the identification of schizophrenia in this population.
Methods: Using data from a clinical multi-centre study, reported symptoms in 26 autistic individuals with intellectual disabilities diagnosed with co-occurring schizophrenia were explored. Scores on two checklists (Psychopathology in Autism Checklist [PAC], Aberrant Behaviour Checklist [ABC]) were compared with two comparison groups: autistic individuals with intellectual disabilities and other mental disorders (94), or no mental disorder (63).
Results: Reported symptoms of schizophrenia in this population met the formal diagnostic criteria. For PAC/ABC scales, only PAC psychosis differed for the schizophrenia group. Among participants with schizophrenia, two were diagnosed with additional mental disorders. Elevated scores for anxiety and depression were common.
Conclusions: Emphasising core symptoms seems necessary when assessing co-occurring schizophrenia in autistic people with intellectual disabilities. The PAC may serve as a helpful screening tool.
(© 2023 The Authors. Journal of Applied Research in Intellectual Disabilities published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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