Follow-up of participants with subjective cognitive decline from Tremembé epidemiologic study, Brazil.

Autor:	César-Freitas KG; Universidade de São Paulo, Faculdade de Medicina, Unidade de Neurologia Cognitiva e Comportamental, Departamento de Neurologia, São Paulo SP, Brazil.; Universidade de Taubaté, Departamento de Medicina, Taubaté SP, Brazil., Berardis ACP; Universidade de Taubaté, Departamento de Medicina, Taubaté SP, Brazil., Pretto TVM; Universidade de Taubaté, Departamento de Medicina, Taubaté SP, Brazil., Viagi AM; Universidade de Taubaté, Departamento de Medicina, Taubaté SP, Brazil., Lourençon V; Universidade de Taubaté, Departamento de Medicina, Taubaté SP, Brazil., Zanini LYK; Universidade de Taubaté, Departamento de Medicina, Taubaté SP, Brazil., Barbosa ICC; Universidade de Taubaté, Departamento de Medicina, Taubaté SP, Brazil., Machado RP; Universidade de Taubaté, Departamento de Medicina, Taubaté SP, Brazil., Cunha NGM; Universidade de Taubaté, Departamento de Medicina, Taubaté SP, Brazil., Watanabe MJL; Universidade de Taubaté, Departamento de Medicina, Taubaté SP, Brazil., Cecchini MA; Universidade de São Paulo, Faculdade de Medicina, Unidade de Neurologia Cognitiva e Comportamental, Departamento de Neurologia, São Paulo SP, Brazil., Brucki SMD; Universidade de São Paulo, Faculdade de Medicina, Unidade de Neurologia Cognitiva e Comportamental, Departamento de Neurologia, São Paulo SP, Brazil., Nitrini R; Universidade de São Paulo, Faculdade de Medicina, Unidade de Neurologia Cognitiva e Comportamental, Departamento de Neurologia, São Paulo SP, Brazil.
Jazyk:	angličtina
Zdroj:	Dementia & neuropsychologia [Dement Neuropsychol] 2023 May 29; Vol. 17, pp. e20220064. Date of Electronic Publication: 2023 May 29 (Print Publication: 2023).
DOI:	10.1590/1980-5764-DN-2022-0064
Abstrakt:	Subjective cognitive decline is defined as a self-perceived cognitive decline but with normal performance in neuropsychological assessments. Objective: To verify the evolution of patients diagnosed with subjective cognitive decline compared to the cognitively normal group without any concern. Methods: This is a follow-up study based on data analysis from the Tremembé epidemiologic study, in Brazil. The 211 individuals classified as cognitively normal and 174 diagnosed as having subjective cognitive decline at baseline were invited to participate. Results: After a median follow-up time of five years, 108 subjective cognitive decline participants (62.0%) were reassessed. Of these, 58 (53.7%) kept this diagnosis, whereas 14 individuals (12.9%) progressed to mild cognitive impairment and 5 (4.6%) to dementia. In the cognitively normal group, 107 (50.7%) were reassessed, of which 51 (47.7%) were still classified likewise, 6 (5.6%) evolved to mild cognitive impairment and 9 (8.4%) to dementia. The presence of cognitive decline had a significant association with increasing age and depression symptoms. Considering the total number of baseline participants in each group: the subjective cognitive decline group showed higher percentage of mild cognitive impairment (p=0.022) and no difference was found in progression to dementia (p=0.468) between the groups after follow-up assessment. Conclusion: Most subjective cognitive decline participants at baseline kept their cognitive complaint at follow-up and this group progressed more to mild cognitive impairment than the other group. No difference in the progression to dementia was found, despite the higher incidence of dementia in the cognitively normal group. Competing Interests: Disclosure: The authors report no conflicts of interest.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu