| Autor: |
Shekim WO, Bylund DB, Alexson J, Glaser RD, Jones SB, Hodges K, Perdue S |
| Jazyk: |
angličtina |
| Zdroj: |
Psychiatry research [Psychiatry Res] 1986 Jun; Vol. 18 (2), pp. 179-88. |
| DOI: |
10.1016/0165-1781(86)90029-6 |
| Abstrakt: |
Platelet monoamine oxidase (MAO) activity was studied in 22 boys diagnosed as having attention deficit disorder with hyperactivity and 12 healthy control boys admitted to a clinical research center and placed on a diet low in monoamines. The hyperactive boys had lower platelet MAO activity than controls, and MAO activity was related to performance on the Matching Familiar Figures Test (MFF) and the Continuous Performance Test (CPT), which yield scores sensitive to impulsivity and inattention. Furthermore, it was negatively related, in hyperactive boys only, to two tests of reading and spelling achievement. Administration of d-amphetamine and placebo in a double-blind crossover design did not significantly raise MAO levels above baseline and was minimally related to improved performance on the MFF and CPT. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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