Visualization of the relationship between electrogustometry and whole mouth test using multidimensional scaling.

Autor: Ha JG; Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Gwangmyeong Hospital, Gwangmyeong-Si, Korea., Kim BR; Department of Medicine, Graduate School, Yonsei University, Seoul, Korea., Cho A; Department of Otorhinolaryngology, Yonsei University College of Medicine, 50-1 Yonsei-Ro, Seodaemun-Gu, Seoul, Korea., Jeong Y; Department of Otorhinolaryngology, Yonsei University College of Medicine, 50-1 Yonsei-Ro, Seodaemun-Gu, Seoul, Korea., Rha MS; Department of Otorhinolaryngology, Yonsei University College of Medicine, 50-1 Yonsei-Ro, Seodaemun-Gu, Seoul, Korea., Kang JW; Department of Otorhinolaryngology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea., Cho HJ; Department of Otorhinolaryngology, Yonsei University College of Medicine, 50-1 Yonsei-Ro, Seodaemun-Gu, Seoul, Korea.; The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Korea.; Korea Mouse Sensory Phenotyping Center, Yonsei University College of Medicine, Seoul, Korea., Yoon JH; Department of Otorhinolaryngology, Yonsei University College of Medicine, 50-1 Yonsei-Ro, Seodaemun-Gu, Seoul, Korea.; The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Korea.; Korea Mouse Sensory Phenotyping Center, Yonsei University College of Medicine, Seoul, Korea.; Global Research Laboratory for Allergic Airway Diseases, Seoul, Korea., Kim CH; Department of Otorhinolaryngology, Yonsei University College of Medicine, 50-1 Yonsei-Ro, Seodaemun-Gu, Seoul, Korea. entman@yuhs.ac.; The Airway Mucus Institute, Yonsei University College of Medicine, Seoul, Korea. entman@yuhs.ac.; Global Research Laboratory for Allergic Airway Diseases, Seoul, Korea. entman@yuhs.ac.; Medical Research Center, Yonsei University College of Medicine, Seoul, Korea. entman@yuhs.ac.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 May 31; Vol. 13 (1), pp. 8798. Date of Electronic Publication: 2023 May 31.
DOI: 10.1038/s41598-023-35372-5
Abstrakt: Interpreting the relationship between different taste function tests of different stimuli, such as chemical and electrical stimulation, is still poorly understood. This study aims to analyze visually as well as quantitatively how to interpret the relationship of results between taste function tests using different stimuli. Patients who underwent the whole mouth test and Electrogustometry (EGM) at a tertiary medical center between August 2018 and December 2018 were reviewed retrospectively with electronic medical records. Of the 110 patients, a total of 86 adults who self-reported that their taste function was normal through a questionnaire were enrolled. EGM measured the thresholds of the chorda tympani (CT) and glossopharyngeal nerve (GL) area of the tongue. The whole mouth test measured detection and recognition thresholds for sweet, salty, bitter, sour, and umami taste. Statistical analyses of Pearson's, Spearman's rank and polyserial correlation and multidimensional scaling (MDS) was performed. The EGM threshold for the average value of both CT regions and the recognition threshold of the whole mouth test were significantly correlated in sweet, salty, bitter, and sour taste (r = 0.244-0.398, P < 0.05), and the detection threshold was correlated only significant in sweet (r = 0.360, P = 0.007). In the MDS analysis results, the three-dimensional (D) solution was chosen over the 2-D solution because of the lower stress. Detection-, recognition threshold of whole mouth test and EGM thresholds of CT and GL area, those were standardized by Z-score, formed well-distinguished sections in the MDS analyses. The EGM threshold of the CT area was closer to the detection and recognition thresholds than the EGM threshold of the GL area. In general, the EGM threshold was closer to the recognition threshold than the detection threshold for each taste. Overall, visualization of the relationship of whole mouth test and EGM by MDS was in good agreement with quantitative analysis. EGM and whole mouth test seem to reflect different aspects of taste. However, when interpreting the EGM results, the EGM threshold of the CT area will show more similarity to the recognition threshold than the detection threshold for the whole mouth test.
(© 2023. The Author(s).)
Databáze: MEDLINE
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