Rifampicin-induced hypertensive urgency: eyes see what the mind knows.

Autor: Gaba M; Internal Medicine, Max Smart Super Speciality Hospital, New Delhi, India manishgaba1990@gmail.com., Kumar N; Internal Medicine, Max Smart Super Speciality Hospital, New Delhi, India., Pandey A; Internal Medicine, Max Smart Super Speciality Hospital, New Delhi, India., Dewan A; Internal Medicine, Max Smart Super Speciality Hospital, New Delhi, India.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2023 May 31; Vol. 16 (5). Date of Electronic Publication: 2023 May 31.
DOI: 10.1136/bcr-2023-254699
Abstrakt: A man had poor control of hypertension throughout 9 months of antituberculosis treatment. He consulted multiple physicians, who kept increasing this blood pressure medicine. Despite that, it was not controlled and he visited emergency many times with hypertensive urgency. When admitted in our care, he was off antituberculosis treatment for 5 days and his blood pressure was back to normal. We attributed it secondary to rifamipicin-induced enzyme induction. Tuberculosis and hypertension both being very common diseases, we report this case to highlight lack of awareness about these important and easily preventable drug interactions.
Competing Interests: Competing interests: None declared.
(© BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE