Abundant dsRNA picobirnaviruses show little geographic or host association in terrestrial systems.

Autor: Knox MA; School of Veterinary Science, Massey University, New Zealand. Electronic address: m.knox@massey.ac.nz., Wierenga J; School of Veterinary Science, Massey University, New Zealand., Biggs PJ; School of Veterinary Science, Massey University, New Zealand; School of Natural Sciences, Massey University, New Zealand., Gedye K; School of Veterinary Science, Massey University, New Zealand., Almeida V; School of Veterinary Science, Massey University, New Zealand., Hall R; Ministry for Primary Industries, New Zealand., Kalema-Zikusoka G; Conservation Through Public Health, Uganda., Rubanga S; Conservation Through Public Health, Uganda., Ngabirano A; Bwindi Development Network, Uganda., Valdivia-Granda W; Orion Integrated Biosciences, USA., Hayman DTS; School of Veterinary Science, Massey University, New Zealand.
Jazyk: angličtina
Zdroj: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2023 Aug; Vol. 112, pp. 105456. Date of Electronic Publication: 2023 May 29.
DOI: 10.1016/j.meegid.2023.105456
Abstrakt: Picobirnaviruses are double-stranded RNA viruses known from a wide range of host species and locations but with unknown pathogenicity and host relationships. Here, we examined the diversity of picobirnaviruses from cattle and gorillas within and around Bwindi Impenetrable Forest National Park (BIFNP), Uganda, where wild and domesticated animals and humans live in relatively close contact. We use metagenomic sequencing with bioinformatic analyses to examine genetic diversity. We compared our findings to global Picobirnavirus diversity using clustering-based analyses. Picobirnavirus diversity at Bwindi was high, with 14 near-complete RdRp and 15 capsid protein sequences, and 497 new partial viral sequences recovered from 44 gorilla samples and 664 from 16 cattle samples. Sequences were distributed throughout a phylogenetic tree of globally derived picobirnaviruses. The relationship with Picobirnavirus diversity and host taxonomy follows a similar pattern to the global dataset, generally lacking pattern with either host or geography.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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