Osteonecrosis of the jaws in patients under osteoporosis treatment: a nine-year experience report.

Autor:	Penoni DC; Departamento de Saúde, Divisão de Odontologia, Hospital Naval de Brasília, Marinha do Brasil, Brasília, DF, Brasil, ciapenoni@gmail.com.; Departamento de Clínica Odontológica, Divisão de Periodontia, Faculdade de Odontologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil., Canellas JVS; INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, Delaware, United States., Silami MANC; Departamento de Clínica Odontológica, Clínica de Estomatologia e Patologia Oral, Marinha do Brasil, Odontoclínica Central da Marinha, Rio de Janeiro, RJ, Brasil., Sader F; Departamento de Clínica Odontológica, Divisão de Periodontia, Marinha do Brasil, Odontoclínica Central da Marinha, Rio de Janeiro, RJ, Brasil., Pimentel GS Neto; Departamento de Clínica Odontológica, Divisão de Implantodontia, Marinha do Brasil, Odontoclínica Central da Marinha, Rio de Janeiro, RJ, Brasil., Leão ATT; Departamento de Clínica Odontológica, Divisão de Periodontia, Faculdade de Odontologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
Jazyk:	angličtina
Zdroj:	Archives of endocrinology and metabolism [Arch Endocrinol Metab] 2023 May 12; Vol. 67 (4), pp. e000612.
DOI:	10.20945/2359-3997000000612
Abstrakt:	Objective: This study aimed to report the experience of medication-related osteonecrosis of the jaws (MRONJ) in osteoporotic patients for nine years, and their associated initiating factors. Materials and Methods: The numbers of invasive oral procedures (IOP) (tooth extraction, dental implant placement, and periodontal procedures) and removable prostheses performed from January 2012 to January 2021 were obtained from the digital records of a large public dental center. There were an estimated 6,742 procedures performed in patients under osteoporosis treatment. Results: Two cases (0.03%) of MRONJ were registered in nine years amongst patients with osteoporosis who had dental treatment at the center. From the 1,568 tooth extractions, one patient (0.06%) developed MRONJ. There was also one case from the 2,139 removable prostheses delivered (0.05%). Conclusion: The prevalence of MRONJ associated with osteoporosis treatment was very low. The protocols adopted seem to be adequate for the prevention of this complication. The findings of this study reinforce the rare frequency of MRONJ associated with dental procedures in patients submitted to the pharmacological management of osteoporosis. An integral analysis of systemic risk factors and oral preventive strategies may be considered regularly in the dental treatment of these patients.
Databáze:	MEDLINE
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