Evaluation of the Correlation between Coronary Artery Disease and Nonalcoholic Fatty Liver Disease: Is There Any Correlation?

Autor:	Momayez Sanat Z; Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Ghorashi SM; Department of MPH, Shiraz School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.; Cardiac Primary Prevention Research Center, Cardiovascular Disease Research Institute, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran., Ajir A; Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran., Fazeli A; Cardiac Primary Prevention Research Center, Cardiovascular Disease Research Institute, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran., Hekmat H; Department of Cardiology, Ziaeian Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Omidi N; Cardiac Primary Prevention Research Center, Cardiovascular Disease Research Institute, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Jazyk:	angličtina
Zdroj:	The journal of Tehran Heart Center [J Tehran Heart Cent] 2023 Jan; Vol. 18 (1), pp. 10-15.
DOI:	10.18502/jthc.v18i1.12576
Abstrakt:	Background: Coronary artery disease (CAD) and nonalcoholic fatty liver disease (NAFLD) are 2 common diseases around the globe. This investigation aimed to evaluate NAFLD prevalence in patients with CAD and the potential association between NAFLD and CAD. Methods: This case-control study was performed between January 2017 and January 2018 at Ziaeian Hospital, Tehran, Iran. All patients aged between 35 and 5 years and referred for myocardial perfusion imaging were selected for the study. Totally, 180 participants were divided into CAD + and CAD - groups. CAD was defined as stenosis of greater than 50.0% in at least 1 coronary artery. Afterward, all the patients underwent abdominal sonography and laboratory tests for NAFLD evaluation. Patients with a history of liver diseases, alcohol consumption, and drug-induced steatosis were excluded. Results: The study population consisted of 122 women (67.8%) and 58 men (32.2%) at a mean age of 49.31±5.42 years. NAFLD was detected in 115 patients. NAFLD prevalence in the CAD + group was 78.9%. NAFLD was determined as an independent risk factor for CAD (OR, 3.9). Conclusion: NAFLD prevalence was high in the CAD + group. The incidence of steatosis is on the rise in the general population. Hence, considering the high prevalence of abdominal obesity, all patients with NAFLD should be evaluated for CAD. (Copyright © 2023 Tehran University of Medical Sciences. Published by Tehran University of Medical Sciences.)
Databáze:	MEDLINE
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