Prolonged generalized immune response on 18 F-FDG PET/CT following COVID-19 vaccination.
| Autor: | Sawant DA; Department of Radiology, Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Razmaria AA; Department of Radiology, Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Pandit-Taskar N; Department of Radiology, Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Radiology case reports [Radiol Case Rep] 2023 May 23; Vol. 18 (8), pp. 2552-2557. Date of Electronic Publication: 2023 May 23 (Print Publication: 2023). |
| DOI: | 10.1016/j.radcr.2023.04.046 |
| Abstrakt: | The Coronavirus disease 2019 (COVID-19) pandemic continues to be a major public health concern affecting millions of people globally. The COVID-19 vaccination has implications in medical assessment of cancer patients especially undergoing diagnostic imaging such as 18 F-fluoro-deoxyglucose (FDG) positron emission tomography with computed tomography (PET/CT). The inflammatory changes following vaccination can cause false positive findings on imaging. We present a case of a patient with esophageal carcinoma who had 18 F-FDG PET/CT scan, 8 weeks following booster dose of Moderna COVID-19 vaccination, which showed widespread FDG avid reactive lymph nodes and intense splenic uptake for prolonged duration of approximately 8 months (34 weeks) probably representing generalized immune response. It is important from radiological/nuclear medicine perspective to recognize imaging features of such rare effect of COVID-19 vaccination, which can pose a challenge in assessing 18 F-FDG PET/CT scans in cancer patients. It has also opened new avenues for future research evaluating such COVID-19 vaccine-related prolonged systemic immunological response in cancer patients. (© 2023 Published by Elsevier Inc. on behalf of University of Washington.) |
| Databáze: | MEDLINE |
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