Patterns of physical activity and SARS-CoV-2 severe pneumonia: A case-control study.

Autor:	Cardoso FJ; Department of Gastroenterology, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Brazil., Fonseca Leal de Araújo CA; Department of Pediatrics, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Brazil., da Silva Junior JR; Department of Postgraduate, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Brazil., Guimarães A; Department of Pediatrics, Hospital Dom Malan (HDM), Brazil., Taveiro MRV; Department of Pediatrics, Universidade do Vale do São Francisco (UNIVASF), Brazil., Alves JGB; Department of Pediatrics, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Brazil. Electronic address: joaoguilherme@imip.org.br.
Jazyk:	English; Spanish; Castilian
Zdroj:	Medicina clinica [Med Clin (Barc)] 2023 Sep 29; Vol. 161 (6), pp. 243-247. Date of Electronic Publication: 2023 May 09.
DOI:	10.1016/j.medcli.2023.04.031
Abstrakt:	Background: Regular physical activity is associated with a low risk of severe community-acquired infections. However, the hypothesis that a physical inactivity pattern is associated with a higher risk for severe COVID-19 has not been completely proven, especially with severe pneumonia. Objective: The goal of this study was to confirm the link between physical activity patterns and severe SARS-CoV-2 pneumonia. Design: Case-control study. Methods: This study involved 307 patients who developed SARS-CoV-2 severe pneumonia and were hospitalized in an intensive care unit. Age- and sex-matched controls (307) were selected from the same population: patients with mild to moderate forms of COVID-19 who were not hospitalized. Physical activity patterns were assessed using the short version of the International Physical Activity Questionnaire. Results: The mean physical activity levels were lower in the SARS-CoV-2 severe pneumonia group as compared to the control group: 1576±2939 vs 2438±2999, metabolic equivalent of task (MET-min/week), p<0.001. A high or moderate physical activity level was more common in the control group, and a low physical activity level was more observed in the case group (p<0.001). Obesity was also associated with severe SARS-CoV-2 pneumonia (p<0.001). Multivariable analysis showed that a low physical activity level was associated with a higher risk for severe SARS-CoV-2 pneumonia, independent of nutritional status (CI 3.7; 2.24-5.99), p<0.001). Conclusion: A higher and moderate level of physical activity is linked to a lower risk of SARS-CoV-2 severe pneumonia. (Copyright © 2023 Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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