20-Month monitoring of SARS-CoV-2 in wastewater of Curitiba, in Southern Brazil.

Autor: Belmonte-Lopes R; Graduate Program On Pathology, Parasitology, and Microbiology, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil.; Basic Pathology Department, Biological Sciences Sector, Microbiological Collections of Paraná Network, Room 135/136. 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil.; Basic Pathology Department, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil., Barquilha CER; Graduate Program On Water Resources and Environmental Engineering, Hydraulics and Sanitation Department, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil.; Hydraulics and Sanitation Department, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil., Kozak C; Environment Department, Maringa State University, SESI Block, 1800 Ângelo Moreira da Fonseca AvenueRoom 15, Parque Danielle, Umuarama, PR, 87506-370, Brazil., Barcellos DS; Hydraulics and Sanitation Department, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil., Leite BZ; Research and Innovation Management, Paraná Sanitation Company (SANEPAR), 1376 Eng. Rebouças St, Rebouças, Curitiba, PR, 80215-900, Brazil., da Costa FJOG; Research and Innovation Management, Paraná Sanitation Company (SANEPAR), 1376 Eng. Rebouças St, Rebouças, Curitiba, PR, 80215-900, Brazil., Martins WL; Basic Pathology Department, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil., Oliveira PE; Hydraulics and Sanitation Department, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil., Pereira EHRA; Hydraulics and Sanitation Department, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil., Filho CRM; Sanitary and Environmental Engineering Department, Federal University of Minas Gerais (UFMG), 6627 Antonio Carlos Avenue, Block 1, Room 4529, Belo Horizonte, MG, 31270-901, Brazil., de Souza EM; Biochemistry and Molecular Biology Department, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil., Possetti GRC; Research and Innovation Management, Paraná Sanitation Company (SANEPAR), 1376 Eng. Rebouças St, Rebouças, Curitiba, PR, 80215-900, Brazil., Vicente VA; Basic Pathology Department, Biological Sciences Sector, Microbiological Collections of Paraná Network, Room 135/136. 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil.; Basic Pathology Department, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil., Etchepare RG; Hydraulics and Sanitation Department, Federal University of Paraná, 100 Coronel Francisco Heráclito Dos Santos Avenue, Curitiba, PR, 81530-000, Brazil. ramiro.etchepare@ufpr.br.
Jazyk: angličtina
Zdroj: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2023 Jul; Vol. 30 (31), pp. 76687-76701. Date of Electronic Publication: 2023 May 27.
DOI: 10.1007/s11356-023-27926-x
Abstrakt: The COVID-19 pandemic resulted in the collapse of healthcare systems and led to the development and application of several approaches of wastewater-based epidemiology to monitor infected populations. The main objective of this study was to carry out a SARS-CoV-2 wastewater based surveillance in Curitiba, Southern Brazil Sewage samples were collected weekly for 20 months at the entrance of five treatment plants representing the entire city and quantified by qPCR using the N1 marker. The viral loads were correlated with epidemiological data. The correlation by sampling points showed that the relationship between the viral loads and the number of reported cases was best described by a cross-correlation function, indicating a lag between 7 and 14 days amidst the variables, whereas the data for the entire city presented a higher correlation (0.84) with the number of positive tests at lag 0 (sampling day). The results also suggest that the Omicron VOC resulted in higher titers than the Delta VOC. Overall, our results showed that the approach used was robust as an early warning system, even with the use of different epidemiological indicators or changes in the virus variants in circulation. Therefore, it can contribute to public decision-makers and health interventions, especially in vulnerable and low-income regions with limited clinical testing capacity. Looking toward the future, this approach will contribute to a new look at environmental sanitation and should even induce an increase in sewage coverage rates in emerging countries.
(© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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