| Autor: |
Ruiz-Gallardo JI; Department of Internal Medicine, Hospital Civil de Guadalajara 'Fray Antonio Alcalde', Guadalajara 44350, Mexico., Cervantes-Pérez E; Department of Internal Medicine, Hospital Civil de Guadalajara 'Fray Antonio Alcalde', Guadalajara 44350, Mexico.; Tlajomulco Universitary Center, Universidad de Guadalajara, Tlajomulco de Zúñiga 44100, Mexico., Pérez de Acha-Chávez A; Department of Geriatrics, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico., Cervantes-Cardona GA; Department of Philosophical, Methodological and Instrumental Disciplines, Health Sciences University Center, Universidad de Guadalajara, Guadalajara 44100, Mexico., Ramírez-Ochoa S; Department of Internal Medicine, Hospital Civil de Guadalajara 'Fray Antonio Alcalde', Guadalajara 44350, Mexico., Nápoles-Echauri A; Department of Geriatrics, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico., González-Ojeda A; Biomedical Research Unit 02, Hospital de Especialidades, Centro Médico Nacional de Occidente, Guadalajara 44350, Mexico., Fuentes-Orozco C; Biomedical Research Unit 02, Hospital de Especialidades, Centro Médico Nacional de Occidente, Guadalajara 44350, Mexico., Hernández-Mora FJ; Department of Human Reproduction, Health Sciences University Center, Universidad de Guadalajara, Guadalajara 44329, Mexico., Gómez-Sánchez E; Division of Clinical Disciplines, Health Sciences University Center, Universidad de Guadalajara, Guadalajara 44100, Mexico., Michel-González JI; Department of Internal Medicine, Hospital Civil de Guadalajara 'Fray Antonio Alcalde', Guadalajara 44350, Mexico., González-Valencia CM; Department of Research Ethics, Hospital Hispano, Guadalajara 44140, Mexico., Cervantes-Guevara G; Department of Welfare and Sustainable Development, Centro Universitario del Norte, Universidad de Guadalajara, Colotlán 46200, Mexico.; Department of Gastroenterology, Hospital Civil de Guadalajara 'Fray Antonio Alcalde', Guadalajara 44350, Mexico. |
| Abstrakt: |
Background and Objectives : Our primary objective was to study the clinical and biochemical characteristics associated with acute kidney injury (AKI) remission in a group of Mexican patients. Materials and methods : We retrospectively enrolled 75 patients who were diagnosed with AKI and separated the sample into two groups: nonremitting patients ( n = 27, 36%) vs. remitting patients ( n = 48, 64%). Results : We found significant relationships between nonremitting AKI and previous diagnosis of chronic kidney disease ( p = 0.009), higher serum creatinine (Cr) at admission ( p < 0.0001), lower estimated glomerular filtration rate (eGFR) ( p < 0.0001), maximum serum creatinine during hospitalization ( p < 0.0001), higher fractional excretion of sodium (FENa) ( p < 0.0003) and 24-h urine protein ( p = 0.005), higher serum potassium on admission ( p = 0.025), abnormal levels of procalcitonin ( p = 0.006), and increased risk of death ( p = 0.015). Conclusion : Chronic kidney disease (CKD), lower eGFR, higher levels of serum creatinine during hospitalization, higher FENa and 24-h urine protein, abnormal levels of procalcitonin, and higher serum potassium on admission were associated with nonremitting AKI. These findings may facilitate the rapid identification of patients at risk for nonremitting AKI based on clinical and biochemical characteristics. Furthermore, these findings may inform the design of timely strategies for the vigilance, prevention, and treatment of AKI. |
