| Autor: |
Prasad M; Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA., Ingolfsland EC; Department of Pediatrics, Division of Neonatology, University of Minnesota, Minneapolis, MN 55455, USA., Christiansen SP; Departments of Ophthalmology and Pediatrics, Boston University Chobanian & Avedisian School of Medicine, Boston Medical Center, Boston, MA 02118, USA. |
| Jazyk: |
angličtina |
| Zdroj: |
Life (Basel, Switzerland) [Life (Basel)] 2023 Apr 24; Vol. 13 (5). Date of Electronic Publication: 2023 Apr 24. |
| DOI: |
10.3390/life13051075 |
| Abstrakt: |
Severe ROP is characterized by the development of retinal fibrovascular proliferation that may progress to retinal detachment. The purpose of this report is to review five of the most common and well-studied perinatal and neonatal modifiable risk factors for the development of severe ROP. Hyperoxemia, hypoxia, and associated prolonged respiratory support are linked to the development of severe ROP. While there is a well-established association between clinical maternal chorioamnionitis and severe ROP, there is greater variability between histologic chorioamnionitis and severe ROP. Neonatal sepsis, including both bacterial and fungal subtypes, are independent predictors of severe ROP in preterm infants. Although there is limited evidence related to platelet transfusions, the risk of severe ROP increases with the number and volume of red blood cell transfusions. Poor postnatal weight gain within the first six weeks of life is also strongly tied to the development of severe ROP. We also discuss preventative strategies that may reduce the risk of severe ROP. Limited evidence-based studies exist regarding the protective effects of caffeine, human milk, and vitamins A and E. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
|
Nepřihlášeným uživatelům se plný text nezobrazuje |
K zobrazení výsledku je třeba se přihlásit.
|
