A thin layer chromatographic method for high volume screening of urine for methylphenidate abuse.

Autor: Manno BR, Manno JE, Dempsey CA
Jazyk: angličtina
Zdroj: Journal of analytical toxicology [J Anal Toxicol] 1986 May-Jun; Vol. 10 (3), pp. 116-9.
DOI: 10.1093/jat/10.3.116
Abstrakt: A thin layer chromatographic (TLC) method for the high volume screening of urine for methylphenidate (Ritalin) abuse is presented. The method utilizes charcoal extraction of ritalinic acid from urine and a simple test-tube methylation step for the conversion of the ritalinic acid to methylphenidate. The methylphenidate is then subjected to a routine TLC drug procedure for subsequent qualitative identification.
Databáze: MEDLINE