| Autor: |
Zhang F; College of Life Sciences, Shandong Normal University, Jinan 250014, China., Neik TX; School of Biosciences, University of Nottingham Malaysia, Semenyih 43500, Malaysia., Thomas WJW; School of Biological Sciences, University of Western Australia, Perth, WA 6009, Australia., Batley J; School of Biological Sciences, Institute of Agriculture, University of Western Australia, Perth, WA 6009, Australia. |
| Jazyk: |
angličtina |
| Zdroj: |
International journal of molecular sciences [Int J Mol Sci] 2023 May 11; Vol. 24 (10). Date of Electronic Publication: 2023 May 11. |
| DOI: |
10.3390/ijms24108623 |
| Abstrakt: |
Genome editing is an important strategy to maintain global food security and achieve sustainable agricultural development. Among all genome editing tools, CRISPR-Cas is currently the most prevalent and offers the most promise. In this review, we summarize the development of CRISPR-Cas systems, outline their classification and distinctive features, delineate their natural mechanisms in plant genome editing and exemplify the applications in plant research. Both classical and recently discovered CRISPR-Cas systems are included, detailing the class, type, structures and functions of each. We conclude by highlighting the challenges that come with CRISPR-Cas and offer suggestions on how to tackle them. We believe the gene editing toolbox will be greatly enriched, providing new avenues for a more efficient and precise breeding of climate-resilient crops. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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