| Autor: |
Carvalho ÉS; School of Health Sciences, Amazonas State University, Manaus 69050030, Amazonas, Brazil.; Department of Teaching and Research, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69040000, Amazonas, Brazil., Oliveira I; Department of BioMolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040903, São Paulo, Brazil., Nascimento TP; School of Health Sciences, Amazonas State University, Manaus 69050030, Amazonas, Brazil.; Department of Teaching and Research, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69040000, Amazonas, Brazil., da Silva Neto AV; School of Health Sciences, Amazonas State University, Manaus 69050030, Amazonas, Brazil.; Department of Teaching and Research, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69040000, Amazonas, Brazil., Leal BAS; School of Health Sciences, Amazonas State University, Manaus 69050030, Amazonas, Brazil., Araújo FQ; School of Health Sciences, Amazonas State University, Manaus 69050030, Amazonas, Brazil., Julião BFV; School of Health Sciences, Amazonas State University, Manaus 69050030, Amazonas, Brazil., Souza ARN; School of Health Sciences, Amazonas State University, Manaus 69050030, Amazonas, Brazil.; Department of Teaching and Research, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69040000, Amazonas, Brazil., Abrahim AW; School of Health Sciences, Amazonas State University, Manaus 69050030, Amazonas, Brazil., Macedo BBO; Department of Teaching and Research, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69040000, Amazonas, Brazil., de Oliveira JTS; Department of Teaching and Research, Alfredo da Matta Foundation, Manaus 69065130, Amazonas, Brazil., Wen FH; Butantan Institute, São Paulo 05501000, São Paulo, Brazil., Pucca MB; Medical School, Federal University of Roraima, Boa Vista 69310000, Roraima, Brazil.; Health Sciences Postgraduate Program, Federal University of Roraima, Boa Vista 69310000, Roraima, Brazil., Monteiro WM; School of Health Sciences, Amazonas State University, Manaus 69050030, Amazonas, Brazil.; Department of Teaching and Research, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69040000, Amazonas, Brazil., Sachett JAG; School of Health Sciences, Amazonas State University, Manaus 69050030, Amazonas, Brazil.; Department of Teaching and Research, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69040000, Amazonas, Brazil.; Department of Teaching and Research, Alfredo da Matta Foundation, Manaus 69065130, Amazonas, Brazil. |
| Abstrakt: |
Envenomation caused by venomous animals may trigger significant local complications such as pain, edema, localized hemorrhage, and tissue necrosis, in addition to complications such as dermonecrosis, myonecrosis, and even amputations. This systematic review aims to evaluate scientific evidence on therapies used to target local effects caused by envenomation. The PubMed, MEDLINE, and LILACS databases were used to perform a literature search on the topic. The review was based on studies that cited procedures performed on local injuries following envenomation with the aim of being an adjuvant therapeutic strategy. The literature regarding local treatments used following envenomation reports the use of several alternative methods and/or therapies. The venomous animals found in the search were snakes (82.05%), insects (2.56%), spiders (2.56%), scorpions (2.56%), and others (jellyfish, centipede, sea urchin-10.26%). In regard to the treatments, the use of tourniquets, corticosteroids, antihistamines, and cryotherapy is questionable, as well as the use of plants and oils. Low-intensity lasers stand out as a possible therapeutic tool for these injuries. Local complications can progress to serious conditions and may result in physical disabilities and sequelae. This study compiled information on adjuvant therapeutic measures and underscores the importance of more robust scientific evidence for recommendations that act on local effects together with the antivenom. |
