| Autor: |
Greenfield C, Osidiana V, Karayiannis P, Galpin S, Musoke R, Jowett TP, Mati P, Tukei PM, Thomas HC |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of medical virology [J Med Virol] 1986 Jun; Vol. 19 (2), pp. 135-42. |
| DOI: |
10.1002/jmv.1890190205 |
| Abstrakt: |
In Kenya hepatitis B virus (HBV) infection and its sequelae are common. We followed up 49 hepatitis B surface antigen (HBsAg)- positive mothers and their newborn infants for 9 months to determine the importance of perinatal transmission in the African and to relate this to the HBe and HBV-DNA status of the mother. Our study shows that perinatal transmission is relatively unimportant in Kenya and that this may be a consequence of the low levels of circulating HBV-DNA in the maternal plasma. These results imply that vaccination without hyperimmune globulin may be adequate to control HBV infection in Kenya. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
Plný text