Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a Healthy Environment and Endocrine Disruptors Strategies Workshop.

Autor: Heindel JJ; Healthy Environment and Endocrine Disruptor Strategies, Boseman, Montana, United States. Electronic address: jerryheindel@gmail.com., Alvarez JA; Department of Medicine, Emory University, Atlanta, GA, United States., Atlas E; Health Canada, Ottawa, Ontario, Canada., Cave MC; Department of Medicine, Pharmacology and Toxicology, Biochemistry and Molecular Genetics, University of Louisville, Lousiville, KY, United States., Chatzi VL; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Collier D; Department of Pediatrics, East Carolina University, Greenville, NC, United States., Corkey B; Chobanian and Avedesian School of Medicine, Boston University, Boston, MA, United States., Fischer D; Environmental Health Sciences, Boseman, MT, United States., Goran MI; Department of Pediatrics, Keck School of Medicine, USC, Los Angeles, CA, United States., Howard S; Healthy Environment and Endocrine Disruptor Strategies, Boseman, Montana, United States., Kahan S; National Center for Weight and Wellness, Johns Hopkins Blumberg School of Public Health, Baltimore, MD, United States., Kayhoe M; Environmental Health Sciences, Boseman, MT, United States., Koliwad S; Department of Medicine, University of California San Francisco, San Francisco, CA, United States., Kotz CM; Department of Integrative Biology and Physiology, University of Minnesota and Minneapolis VA Health Care System, Minneapolis, MN, United States., La Merrill M; Department of Environmental Toxicology, University of California, Davis, CA, United States., Lobstein T; World Obesity Federation, London, United Kingdom., Lumeng C; Department of Pediatrics, University of Michigan Medical School, University of Michigan, Ann Arbor, MI, United States., Ludwig DS; New Balance Foundation Obesity Prevention Center, Boston Children's Hospital, Boston, MA, United States., Lustig RH; Department of Physiology, Miguel Hernandez University of Elche, Elche, Spain., Myers P; Environmental Health Sciences, Boseman, MT, United States., Nadal A; Department of Physiology, Miguel Hernandez University of Elche, Elche, Spain., Trasande L; Department of Pediatrics, New York University Langone Health, New York, NY, United States; Department of Population Health, New York University Langone Health, New York, NY, United States., Redman LM; Department of Reproductive Endocrinology & Women's Health, Pennington Biomedical Research Center, Baton Rouge, LA, United States., Rodeheffer MS; Department of Comparative Medicine, Yale University, New Haven, CT, United States., Sargis RM; Department of Endocrinology, Diabetes and Metabolism, University of Illinois at Chicago, Chicago, IL, United States., Stephens JM; Department of Pediatrics, New York University Langone Health, New York, NY, United States., Ziegler TR; Department of Medicine, Emory University, Atlanta, GA, United States., Blumberg B; Department of Developmental and Cell BiologyUniversity of California Irvine, Irvine, CA, United States.
Jazyk: angličtina
Zdroj: The American journal of clinical nutrition [Am J Clin Nutr] 2023 Jul; Vol. 118 (1), pp. 329-337. Date of Electronic Publication: 2023 May 23.
DOI: 10.1016/j.ajcnut.2023.05.024
Abstrakt: On September 7 and 8, 2022, Healthy Environment and Endocrine Disruptors Strategies, an Environmental Health Sciences program, convened a scientific workshop of relevant stakeholders involved in obesity, toxicology, or obesogen research to review the state of the science regarding the role of obesogenic chemicals that might be contributing to the obesity pandemic. The workshop's objectives were to examine the evidence supporting the hypothesis that obesogens contribute to the etiology of human obesity; to discuss opportunities for improved understanding, acceptance, and dissemination of obesogens as contributors to the obesity pandemic; and to consider the need for future research and potential mitigation strategies. This report details the discussions, key areas of agreement, and future opportunities to prevent obesity. The attendees agreed that environmental obesogens are real, significant, and a contributor at some degree to weight gain at the individual level and to the global obesity and metabolic disease pandemic at a societal level; moreover, it is at least, in theory, remediable.
(Copyright © 2023 American Society for Nutrition. All rights reserved.)
Databáze: MEDLINE