Incidence and risk factors of abdominal compartment syndrome in pediatric oncology patients: a prospective cohort study.

Autor: Pinto GCC; Universidade de São Paulo, São Paulo, Brazil. gabrielaccpinto@gmail.com., Gaiga LC; Universidade de São Paulo, São Paulo, Brazil., de Moura MP; Universidade de São Paulo, São Paulo, Brazil., Troster EJ; Universidade de São Paulo, São Paulo, Brazil.
Jazyk: angličtina
Zdroj: European journal of pediatrics [Eur J Pediatr] 2023 Aug; Vol. 182 (8), pp. 3611-3617. Date of Electronic Publication: 2023 May 25.
DOI: 10.1007/s00431-023-05013-0
Abstrakt: Abdominal compartment syndrome (ACS) has been the subject of increasing research over the past decade owing to its effects on morbidity and mortality in critically ill patients. This study aimed to determine the incidence and risk factors of ACS in patients in an onco-hematological pediatric intensive care unit in a middle-income country and to analyze patient outcomes. This prospective cohort study was conducted between May 2015 and October 2017. Altogether, 253 patients were admitted to the PICU, and 54 fulfilled the inclusion criteria for intra-abdominal pressure (IAP) measurements. IAP was measured using the intra-bladder indirect technique with a closed system (AbViser AutoValve ® , Wolfle Tory Medical Inc., USA) in patients with clinical indications for indwelling bladder catheterization. Definitions from the World Society for ACS were used. The data were entered into a database and analyzed. The median age was 5.79 years, and the median pediatric risk of mortality score was 7.1. The incidence of ACS was 27.7%. Fluid resuscitation was a significant risk factor for ACS in the univariate analysis. The mortality rates in the ACS and non-ACS groups were 46.6% and 17.9%, respectively (P < 0.05). This is the first study of ACS in critically ill children with cancer.   Conclusion: The incidence and mortality rates were high, justifying IAP measurement in children with ACS risk factors.
(© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje