Direct oral anticoagulant drugs for the management of venous thromboembolism.

Autor: Thanavaro JL; Joanne L. Thanavaro is a professor of nursing and Associate Dean for Graduate Education at Saint Louis University Trudy Busch Valentine School of Nursing in St. Louis, Mo.
Jazyk: angličtina
Zdroj: The Nurse practitioner [Nurse Pract] 2023 Jun 01; Vol. 48 (6), pp. 27-35.
DOI: 10.1097/01.NPR.0000000000000060
Abstrakt: Abstract: Direct oral anticoagulants (DOACs) are effective for both prevention and treatment of venous thromboembolism (VTE) and have favorable safety in comparison with warfarin. Although drug-drug interactions with DOACs are not as frequent as with warfarin, certain drugs can interfere with DOAC metabolism, affect DOAC efficacy, and potentially cause adverse reactions when used in combination with DOACs. The NP must determine which agent is most beneficial for the individual patient with VTE based on a number of factors. A knowledge of periprocedural management of DOACs will assist the NP in providing a smooth transition for patients undergoing minor and major procedures and surgeries.
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Databáze: MEDLINE