Structural elucidation of lactone derivatives from Dendrobium pendulum.

Autor: Zhang MS; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, China., Jiang Y; Department of Nursing, Sichuan Nursing Vocational College, Deyang, China., Cheng L; Department of Pharmacy, The First People's Hospital of Bijie City, Bijie, China., Yang JW; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, China., Dong MJ; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, China., Sun CX; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, China., Xiao SJ; Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, China.
Jazyk: angličtina
Zdroj: Magnetic resonance in chemistry : MRC [Magn Reson Chem] 2023 Aug; Vol. 61 (8), pp. 481-486. Date of Electronic Publication: 2023 May 25.
DOI: 10.1002/mrc.5370
Abstrakt: Six lactone derivatives, including four α-pyrones derivatives (1-4), two α-furanone derivatives (5 and 6), were isolated from the Dendrobium pendulum. Structural elucidation of these undescribed lactone derivatives were accomplished on the basis of detailed nuclear magnetic resonance analysis, and the absolute configurations of compounds 1-4 were confirmed by electronic circular dichroism (ECD) techniques. The cytotoxic effects of isolated compounds on human breast cancer cell MDA-MB-231 were evaluated by the MTT assay.
(© 2023 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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