Common Orthopedic Traits and Screening for Breeding Programs.
| Autor: | Hayward JJ; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA., Todhunter RJ; Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA. Electronic address: rjt2@cornell.edu. |
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| Jazyk: | angličtina |
| Zdroj: | The Veterinary clinics of North America. Small animal practice [Vet Clin North Am Small Anim Pract] 2023 Sep; Vol. 53 (5), pp. 1013-1029. Date of Electronic Publication: 2023 May 22. |
| DOI: | 10.1016/j.cvsm.2023.04.004 |
| Abstrakt: | Orthopedic diseases are complex traits, meaning genetics and environmental factors affect risk, making identification of genetic associations difficult. In the United States, hip and elbow scores, patellar luxation scores, Legg-Calvé-Perthes disease, and shoulder osteochondrosis affectedness are available in the Orthopedic Foundation for Animals registry. Distraction indices and extended, ventrodorsal hip conformation scores are recorded by PennHIP. Application of estimated breeding values for hip and elbow dysplasia in breeder selection reduces the severity and prevalence of these traits. Genomic prediction and whole-genome sequence technologies and methods should improve knowledge of genetics underlying orthopedic diseases, leading to improved canine orthopedic genetic quality. (Copyright © 2023 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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