Echocardiographic Correlates of Left Atrial Function Index Among Hypertensive Heart Failure Patients: A Cross-Sectional Study.

Autor:	Kweki AG; Internal Medicine/Cardiology, Colchester Hospital, Colchester, GBR., Aiwuyo HO; Internal Medicine, Brookdale University Hospital Medical Center, Brooklyn, USA., Umuerri EM; Medicine, Delta State University, Abraka, NGA.; Internal Medicine/Cardiology, Delta State University Teaching Hospital, Oghara, NGA., Aghwana R; Internal Medicine, Colchester General Hospital, Colchester, GBR., Oladimeji OM; Medicine, Lagos State University Teaching Hospital Hospital, Lagos, NGA., Iloeje UN; Internal Medicine/Cardiology, Federal Medical Centre, Yenagoa, NGA., Aigbe FI; Internal Medicine/Cardiology, Delta State University, Abraka, NGA., Obasohan A; Medicine, College of Medical Sciences, University of Benin, Benin City, NGA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Apr 23; Vol. 15 (4), pp. e38013. Date of Electronic Publication: 2023 Apr 23 (Print Publication: 2023).
DOI:	10.7759/cureus.38013
Abstrakt:	Background Heart failure contributes to the global burden of cardiovascular diseases, with hypertensive heart failure affecting individuals in their productive age group and leading to high economic losses and disability-adjusted life years. The left atrium, on the other hand, contributes significantly to left ventricular filling in heart failure patients, and the left atrial function index is an excellent tool for assessing left atrial function among heart failure patients. The study aimed to evaluate some parameters of systolic and diastolic function as correlates and potential predictors of the left atrial function index among hypertensive heart failure cohorts. Materials and methods The study was conducted at Delta State University Teaching Hospital, Oghara. Eighty (80) patients with hypertensive heart failure who met the inclusion criteria were enrolled in the cardiology outpatient clinics. The left atrial function index was calculated using the following formula: LAFI = (LAEF x LVOT-VTI)/LAESVI. (LAFI = left atrial function index; LAEF = left atrial emptying fraction; LAESVI = left atrial end-systolic volume index; LVOTVTI = outflow tract velocity time integral). The data were analysed using IBM Statistical Product and Service Solution Version 22. Relationships between variables were determined using analysis of variance, Pearson correlation, and multiple linear regressions. Significance was assessed at p<0.05. Result It was discovered that the left atrial function index correlated with ejection fraction (r = 0.616, p = 0.001), fractional shortening (r = 0.462, p = 0.001), and the ratio of early transmitral flow to early myocardial contractility, E/E' (r = -0.522, p = 0.001). However, there was no correlation with stroke volume (r = 0.38, p = 0.11); the ratio of early transmitral flow to late transmitral flow, E/A (r = -0.10, p = 0.11); isovolumetric relaxation time, IVRT (r = -0.171, p = 0.11); and tricuspid annular plane systolic excursion, TAPSE (r = 0.185, p = 0.10). Of the variables that correlated with left atrial function index, left ventricular ejection fraction and the ratio of early transmitral flow to early myocardial contractility (E/E') were found to be independent predictors of left atrial function index. Conclusion Left ventricular ejection fraction and the ratio of early transmitral flow to early myocardial contractility reflect changes in the left atrial function index, and as such, they should be used as surrogates for its assessment, especially in low- and medium-income countries where left atrial function index estimation is not routinely done. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Kweki et al.)
Databáze:	MEDLINE
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