Spiny Keratoderma in Association with Melanoma.

Autor: Pukhalskaya T; Department of Pathology, Dermatopathology and Oral Pathology Services, University of California San Francisco, San Francisco, CA 94115, USA., Mully TW; Department of Pathology, Dermatopathology and Oral Pathology Services, University of California San Francisco, San Francisco, CA 94115, USA., Wei ML; Department of Dermatology, University of California San Francisco, San Francisco, CA 94115, USA.
Jazyk: angličtina
Zdroj: Dermatopathology (Basel, Switzerland) [Dermatopathology (Basel)] 2023 May 22; Vol. 10 (2), pp. 142-146. Date of Electronic Publication: 2023 May 22.
DOI: 10.3390/dermatopathology10020021
Abstrakt: Spiny keratoderma (SK) was first described by Brown in 1871 and is characterized by numerous 1-2 mm spines of keratin on the palms and soles, usually sparing the dorsal surfaces, or disseminated over the trunk. Histologically, the "spine" represents a column of hyperkeratosis. Several different forms are known, including familial, sporadic, post-inflammatory and paraneoplastic. Although an association of SK with melanoma has been reported, the significance of such co-occurrence remains unclear due to the limited number of cases. To increase the body of knowledge and shed further light on this rare condition, we present a case of SK in a patient with a recent history of melanoma in situ.
Databáze: MEDLINE
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