Primary pancreatic synovial sarcoma: Report of a rare case and review of the literature.

Autor:	Ali RM; Deparment of Oncology, Hiwa Hospital, Sulaimani, Kurdistan 46000, Iraq., Seerwan K; College of Medicine, University of Sulaimani, Sulaimani, Kurdistan 46000, Iraq., Ali SM; Deparment of Oncology, Hiwa Hospital, Sulaimani, Kurdistan 46000, Iraq., Abdullah AM; Department of Pathology, Sulaimani Teaching Hospital, Sulaimani, Kurdistan 46000, Iraq.; Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46000, Iraq., Hawrami O; Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46000, Iraq., Hussein DM; Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46000, Iraq., Mohammed BJ; Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46000, Iraq.; Department of Medicine, Shar Hospital, Sulaimani, Kurdistan 46000, Iraq., Karim M; Kscien Organization for Scientific Research (Middle East Office), Sulaimani, Kurdistan 46000, Iraq., Abdullah F; Kscien Organization for Scientific Research (Middle East Office), Sulaimani, Kurdistan 46000, Iraq., Abdalla BA; Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46000, Iraq.; Kscien Organization for Scientific Research (Middle East Office), Sulaimani, Kurdistan 46000, Iraq., Kakamad FH; College of Medicine, University of Sulaimani, Sulaimani, Kurdistan 46000, Iraq.; Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46000, Iraq.; Kscien Organization for Scientific Research (Middle East Office), Sulaimani, Kurdistan 46000, Iraq.
Jazyk:	angličtina
Zdroj:	Medicine international [Med Int (Lond)] 2023 Mar 24; Vol. 3 (3), pp. 22. Date of Electronic Publication: 2023 Mar 24 (Print Publication: 2023).
DOI:	10.3892/mi.2023.82
Abstrakt:	Synovial sarcoma is a mesenchymal spindle cell tumor. Primary pancreatic sarcomas are extremely rare. The present study describes a rare case of synovial sarcoma in the head of the pancreas. A 35-year-old male presented with left upper quadrant abdominal pain. An endoscopic ultrasound examination revealed a complex solid-cystic lesion in the pancreatic head. He had undergone pancreaticoduodenectomy (Whipple procedure). A histological examination yielded negative results for AE1/AE3, CD10, S100, CD34, desmin, smooth muscle actin, β-catenin, CD117, HMB45, chromogranin and synaptophysin. However, the results were positive for TLEI and vimentin, which is consistent with synovial sarcoma. Synovial sarcoma is a soft tissue malignant tumor. Primary pancreatic sarcomas frequently present as large, high-grade tumors in the pancreatic head. Histologically, there are several types of synovial sarcoma, such as monophasic, biphasic and poorly differentiated. A histological examination is necessary for the diagnosis as the imaging findings are not specifically suggestive of synovial sarcoma. The preferred course of treatment is complete resection with wide margins, followed by adjuvant chemotherapy and/or radiotherapy. Primary mesenchymal tumors of the pancreas are extremely uncommon. As a result, a diagnosis requires careful evaluation. Surgical resection is the main modality of treatment. Competing Interests: The authors declare that they have no competing interests. (Copyright: © Ali et al.)
Databáze:	MEDLINE
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