A randomized controlled trial of eplerenone in asymptomatic phospholamban p.Arg14del carriers.

Autor: de Brouwer R; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., Te Rijdt WP; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands.; Department of Genetics, Erasmus University Medical Centre, Rotterdam, the Netherlands., Hoorntje ET; Netherlands Heart Institute, Utrecht, the Netherlands.; Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Amin A; Department of Cardiology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, Amsterdam, the Netherlands., Asselbergs FW; Department of Cardiology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, Amsterdam, the Netherlands.; Department of Cardiology, Division Heart & Lungs, Utrecht University Medical Centre, Utrecht, the Netherlands.; Institute of Cardiovascular Science and Institute of Health Informatics, Faculty of Population Health Sciences, University College London, London, UK., Cox MGPJ; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., van der Heijden JF; Department of Cardiology, Division Heart & Lungs, Utrecht University Medical Centre, Utrecht, the Netherlands.; Department of Cardiology, Haga Teaching Hospital, The Hague, the Netherlands., Hillege H; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Karper JC; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Mahmoud B; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., van der Meer P; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Oomen A; Department of Cardiology, Antonius Hospital, Sneek, the Netherlands., Te Riele ASJM; Department of Cardiology, Division Heart & Lungs, Utrecht University Medical Centre, Utrecht, the Netherlands., Silljé HHW; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Tan HL; Netherlands Heart Institute, Utrecht, the Netherlands.; Department of Cardiology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, Amsterdam, the Netherlands., van Tintelen JP; Netherlands Heart Institute, Utrecht, the Netherlands.; Department of Genetics, University of Utrecht, Utrecht University Medical Centre, Utrecht, the Netherlands., van Veldhuisen DJ; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Westenbrink BD; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Wiesfeld ACP; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Willems TP; Department of Radiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., van der Zwaag PA; Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Wilde AAM; Department of Cardiology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, Amsterdam, the Netherlands., de Boer RA; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.; Department of Cardiology, Erasmus University Medical Centre, P.O. Box 2040, 3000 CA Rotterdam, the Netherlands., van den Berg MP; Department of Cardiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Jazyk: angličtina
Zdroj: European heart journal [Eur Heart J] 2023 Oct 21; Vol. 44 (40), pp. 4284-4287.
DOI: 10.1093/eurheartj/ehad292
Abstrakt: Competing Interests: Conflict of interest: R.A.d.B. is president-elect of the Dutch Cardiac Society (NVVC), member of the Executive Committee of the DELIVER-trial and has received grants from AstraZeneca, Abbott, Boehringer Ingelheim, Cardior Pharmaceuticals GmbH, Ionis Pharmaceuticals, Inc., Novo Nordisk, and Roche in the last 36 months. R.A.d.B. has received payment or honoraria from Abbott, AstraZeneca, Bayer, Bristol Myers Squibb, Novartis, and Roche in the last 36 months. J.P.v.T. has received consulting fees from StrideBio in the last 36 months. A.A.M.W. has received grants from the Dutch Heart Foundation and consulting fees from LQT Therapeutics and ARMGO in the last 36 months. A.A.M.W. additionally is a member of the advisory board of the Leap Trial.
Databáze: MEDLINE