MERS-CoV‒Specific T-Cell Responses in Camels after Single MVA-MERS-S Vaccination.

Autor: Meyer Zu Natrup C, Schünemann LM, Saletti G, Clever S, Herder V, Joseph S, Rodriguez M, Wernery U, Sutter G, Volz A
Jazyk: angličtina
Zdroj: Emerging infectious diseases [Emerg Infect Dis] 2023 Jun; Vol. 29 (6), pp. 1236-1239.
DOI: 10.3201/eid2906.230128
Abstrakt: We developed an ELISPOT assay for evaluating Middle East respiratory syndrome coronavirus (MERS-CoV)‒specific T-cell responses in dromedary camels. After single modified vaccinia virus Ankara-MERS-S vaccination, seropositive camels showed increased levels of MERS-CoV‒specific T cells and antibodies, indicating suitability of camel vaccinations in disease-endemic areas as a promising approach to control infection.
Databáze: MEDLINE