Birdshot Chorioretinitis in Patients Aged 80 and Older.

Autor: Debillon L; Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France., Thorne JE; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Bousquet E; Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France., Duraffour P; Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France., Kecili S; Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France., Monnet D; Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France., Brézin AP; Université Paris Cité, Centre d'ophtalmologie de l'Assistance Publique - Hôpitaux de Paris, Paris, France.
Jazyk: angličtina
Zdroj: Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Sep; Vol. 32 (7), pp. 1212-1217. Date of Electronic Publication: 2023 May 19.
DOI: 10.1080/09273948.2023.2215322
Abstrakt: Purpose: To assess the manifestations of birdshot chorioretinitis (BSCR) in patients aged 80 and over.
Design: Among patients with BSCR followed in the CO-BIRD prospective cohort (ClinicalTrials.gov Identifier: NCT05153057), we analyzed the subgroup of patients aged 80 and over.
Methods: Patients were assessed in a standardized manner. Confluent atrophy was defined as hypoautofluorescent spots on fundus autofluorescence (FAF).
Results: We included 39 (8.8%) of the 442 enrolled CO-BIRD patients. The mean age was 83.8 ± 3.7 years. The mean logMAR BCVA was 0.52 ± 0.76, with 30 patients (76.9%) having 20/40 or better in at least one eye. Thirty-five (89.7%) patients were receiving no treatment. Confluent atrophy in the posterior pole, disrupted retrofoveal ellipsoid zone and choroidal neovascularization were associated with logMAR BCVA >0.3 ( p  < .0001).
Conclusion: In patients aged 80 and over we observed a striking heterogeneity of outcomes, but most retained a BCVA that allowed them to drive.
Databáze: MEDLINE
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