The effect of exercise post vertebral augmentation in osteoporotic patients: A systematic review and meta-analysis.

Autor: Than CA; St George's University of London, London, UK.; University of Nicosia Medical School, University of Nicosia, Nicosia, Cyprus.; School of Biomedical Sciences, The University of Queensland, St Lucia, Queensland, Australia., Adra M; St George's University of London, London, UK.; University of Nicosia Medical School, University of Nicosia, Nicosia, Cyprus., Curtis TJ; St George's University of London, London, UK.; University of Nicosia Medical School, University of Nicosia, Nicosia, Cyprus., Shi A; St George's University of London, London, UK.; University of Nicosia Medical School, University of Nicosia, Nicosia, Cyprus., Kim GE; St George's University of London, London, UK.; University of Nicosia Medical School, University of Nicosia, Nicosia, Cyprus., Nakanishi H; St George's University of London, London, UK.; University of Nicosia Medical School, University of Nicosia, Nicosia, Cyprus., Matar RH; St George's University of London, London, UK.; University of Nicosia Medical School, University of Nicosia, Nicosia, Cyprus.; Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA., Brown JMM; School of Biomedical Sciences, The University of Queensland, St Lucia, Queensland, Australia., Dannawi Z; Mid and South Essex NHS Foundation Trust, Basildon, UK., Beck BR; School of Health Sciences and Social Work, Menzies Health Institute Queensland, Gold Coast, Queensland, Australia.; The Bone Clinic Pty Ltd, Brisbane, Queensland, Australia.
Jazyk: angličtina
Zdroj: Journal of orthopaedic research : official publication of the Orthopaedic Research Society [J Orthop Res] 2023 Dec; Vol. 41 (12), pp. 2703-2712. Date of Electronic Publication: 2023 May 30.
DOI: 10.1002/jor.25631
Abstrakt: This meta-analysis investigated the effects of exercise on Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) scores following vertebroplasty or kyphoplasty in osteoporotic fractures. A literature search of PubMed, EMBASE (Elsevier), CiNAHL, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Scopus, and Web of Science was conducted from database inception to October 6, 2022. Eligible studies reported osteoporosis patients over 18 years of age with a diagnosis of at least one vertebral fracture via radiography or clinical assessment. This review was registered in PROSPERO (ID: CRD42022340791). Ten studies met the eligibility criteria (n = 889). VAS scores at baseline were 7.75 (95% CI: 7.54, 7.97, I 2  = 76.11%). Following initiation of exercise, VAS scores at the endpoint of 12 months were 1.91 (95% CI: 1.53, 2.29, I 2  = 92.69%). ODI scores at baseline were 68.66 (95% CI: 56.19, 81.13, I 2  = 85%). Following initiation of exercise, ODI scores at the endpoint of 12 months were 21.20 (95% CI: 14.52, 27.87, I 2  = 99.30). A two-arm analysis demonstrated improved VAS and ODI for the exercise group compared to non-exercise control at 6 months (MD = -0.70, 95% CI: -1.08, -0.32, I 2  = 87% and MD = -6.48, 95% CI: -7.52, -5.44, I 2  = 46%, respectively) and 12 months (MD = -0.88, 95% CI: -1.27, -0.49, I 2  = 85% and MD = -9.62, 95% CI: -13.24, -5.99, I 2  = 93%). Refracture was the only adverse event reported and occurred almost twice as frequently in the non-exercise group than in the exercise group. Exercise rehabilitation post vertebral augmentation is associated with improved pain and functionality, particularly after 6 months of exposure, and may reduce refracture rate.
(© 2023 The Authors. Journal of Orthopaedic Research® published by Wiley Periodicals LLC on behalf of Orthopaedic Research Society.)
Databáze: MEDLINE
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